Chemical Engineering April 2023 - 47

production layout. - Stand 1519
- Optima packaging group GmbH,
Schwäbisch Hall, Germany
www.optima-packaging.com
Major expansion of facility for
manufacturing drug substances
Last December, this company officially
opened (photo) its £6-million
project expansion project in Alnwick,
U.K. The new facility provides a stateof-the-art
drug-substance manufacturing
capability that can deliver integrated
support for drug-candidate
selection through to early clinical
development and beyond. The expansion
delivers multipurpose capacity
of up to 15 GMP reactor streams
with reactor volumes ranging from 5
to 150 L, and tactical deployment of
batch or continuous-flow chemistry
technologies to optimize drug substance
manufacturing processes. The
facility has been designed adopting
Industry 4.0 principles, with the inclusion
of a predictive process control
system (PharmaMV), improving the
transfer from small-scale process research
and development (PR&D) into
manufacture of multi-kilogram quantities
of drug substance for clinical use.
- Stand 1260 - Quotient Sciences,
Nottingham, U.K.
www.quotientsciences.com
A one-stop shop for
product inspection systems
This company supplies a number of
product-inspection systems, offering
Safeline metal detectors and x-ray
inspection systems, Hi-Speed inline
checkweighers, CI-Vision vision systems
and PCE Track & Trace, serialization
and aggregation solutions. For example,
the company will demonstrate
its newest x-ray inspection system,
the X34C, which has an optimized
focal distance to enhance detection of
dense physical contaminants of individually
wrapped pharmaceutical products
at high line speeds. Its compact
design, only 700 mm in length, can be
installed into the smallest of spaces to
avoid line constraints when space is at
a premium. The company also offers
systems to mark packs with individual
serial numbers for full traceability of
the production or packaging process
and to collect critical corresponding
process data. All packaging formats
- from single cartons and bundles
to shipping cases and ready-to-ship
pallets - can be marked and verified.
The company also offers connectivity
and data-management solutions and
global service support. Stand 2361
- Mettler Toledo Product Inspection,
Lutz, Fla.
www.mt.com/pi
Combining multiple operations
into a single machine
The TwinPro technology (photo) combines
two separate batch oral-solid
dosage (OSD) processes - highshear
granulation and fluidized-bed
drying - into a single process unit
running on a single machine. This
combination leads to reduced process
space, less capital equipment investment,
an overall reduction in process
time and total elimination of open
product transfer. These advantages
make it suitable for containment applications.
Also being exhibited is the
MultiLab, the newest laboratory-scale
innovation that incorporates multiple
OSD processes into a single R&D unit.
This is a modular concept, which includes
the primary main module with
a variety of optional process modules,
including fluidized bed, high-shear
granulation, milling, tablet coating and
blending technologies. The MultiLab is
available for both aqueous and solvent
process applications, and solutions
are available for containment applications
and WIP. Stand 1329A - Glatt
Air Techniques Inc., Ramsey, N.J.
www.glatt.com
Consistently homogenize and
emulsify product with this unit
The Quadro Ytron Z Emulsifier (photo)
is said to deliver unparalleled consistency
and control of high-shear process
applications, such as immisciblephase
emulsifying and homogenizing,
wet grinding, deagglomeration and
fine solids dispersing. Incorporating
up to three sets of toothed rotor/stator
heads, the Z Emulsifier processes
product while passing multiple shear
zones in a single-pass. The result is
consistent, repeatable quality at capacities
exceeding conventional multipass
technology. Stand 2437 - IDEX
MPT, Inc., Waterloo, Ont., Canada
www.idex-mpt.com
n
Gerald Ondrey
CHEMICAL ENGINEERING WWW.CHEMENGONLINE.COM
APRIL 2023
47
Quotient Sciences
Glatt Air Techniques
IDEX MPT
http://www.optima-packaging.com http://www.mt.com/pi http://www.quotientsciences.com http://www.glatt.com http://www.idex-mpt.com http://WWW.CHEMENGONLINE.COM
Chemical Engineering April 2023

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