Chemical Engineering June 2018 - 82

FIGURE 2. Importing the data into a platform such as Excel provides the means to extract
the relevant CPPs, but the process is tedious
fail to meet specifications and are
discarded. Running a replacement
batch delays the schedule by at least
two shifts.
The recipe for Product A has
five main steps where ingredients
are added, and then the reactor is
heated and cooled. Process experts
have identified six CPPs that need to
FIGURE 3. With some effort, a spreadsheet can help generate
graphs of the specific CPPs so they can be compared directly
against each other
be controlled within specified limits
during the unit procedure for a batch
to meet specifications. The process
is generally stable and controllable
enough to run within the lines most of
the time.
Nonetheless, some batches fail to
meet the specifications, even while
apparently keeping CPPs " in spec. "
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Chemical Engineering June 2018

Table of Contents for the Digital Edition of Chemical Engineering June 2018

Contents
Chemical Engineering June 2018 - Cover1
Chemical Engineering June 2018 - Cover2
Chemical Engineering June 2018 - Contents
Chemical Engineering June 2018 - 2
Chemical Engineering June 2018 - 3
Chemical Engineering June 2018 - 4
Chemical Engineering June 2018 - 5
Chemical Engineering June 2018 - 6
Chemical Engineering June 2018 - 7
Chemical Engineering June 2018 - 8
Chemical Engineering June 2018 - 9
Chemical Engineering June 2018 - 10
Chemical Engineering June 2018 - 11
Chemical Engineering June 2018 - 12
Chemical Engineering June 2018 - 13
Chemical Engineering June 2018 - 14
Chemical Engineering June 2018 - 15
Chemical Engineering June 2018 - 16
Chemical Engineering June 2018 - 17
Chemical Engineering June 2018 - 18
Chemical Engineering June 2018 - 19
Chemical Engineering June 2018 - 20
Chemical Engineering June 2018 - 21
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Chemical Engineering June 2018 - 23
Chemical Engineering June 2018 - 24
Chemical Engineering June 2018 - 25
Chemical Engineering June 2018 - 26
Chemical Engineering June 2018 - 27
Chemical Engineering June 2018 - 28
Chemical Engineering June 2018 - 29
Chemical Engineering June 2018 - 30
Chemical Engineering June 2018 - 31
Chemical Engineering June 2018 - 32
Chemical Engineering June 2018 - 33
Chemical Engineering June 2018 - 34
Chemical Engineering June 2018 - 35
Chemical Engineering June 2018 - 36
Chemical Engineering June 2018 - 37
Chemical Engineering June 2018 - 38
Chemical Engineering June 2018 - 39
Chemical Engineering June 2018 - 40
Chemical Engineering June 2018 - 41
Chemical Engineering June 2018 - 42
Chemical Engineering June 2018 - 43
Chemical Engineering June 2018 - 44
Chemical Engineering June 2018 - 45
Chemical Engineering June 2018 - 46
Chemical Engineering June 2018 - 47
Chemical Engineering June 2018 - 48
Chemical Engineering June 2018 - 49
Chemical Engineering June 2018 - 50
Chemical Engineering June 2018 - 51
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Chemical Engineering June 2018 - 53
Chemical Engineering June 2018 - 54
Chemical Engineering June 2018 - 55
Chemical Engineering June 2018 - 56
Chemical Engineering June 2018 - 57
Chemical Engineering June 2018 - 58
Chemical Engineering June 2018 - 59
Chemical Engineering June 2018 - 60
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Chemical Engineering June 2018 - 62
Chemical Engineering June 2018 - 63
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Chemical Engineering June 2018 - 65
Chemical Engineering June 2018 - 66
Chemical Engineering June 2018 - 67
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Chemical Engineering June 2018 - 70
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Chemical Engineering June 2018 - 73
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Chemical Engineering June 2018 - Cover3
Chemical Engineering June 2018 - Cover4
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