www.chemengonline.com may 2016 Cover Story 42 Part 1 Mixers: Four Innovations Worth a Closer Look Many factors can impact the success of mixing in chemical process operations. The design breakthroughs profiled here address some of the most commonly encountered issues 50 Part 2 Reliable Operation and Sealing of Agitators Mechanical seals, as required by most vessel agitators, are systems sufficiently complex to warrant a good understanding by engineers and good training for operators In the News 7 Chementator Making complex silicone parts by 3-D printing; Syngas-to-lipids process demonstrated; A joint effort to enable the production of sulfur-enhanced urea at large scale; Microbes make a meal of PET; Extremophilic algae selectively recover precious metals from solution; and more 14 Business News TCV begins construction of new liquid polybutadiene plant in France; Vertellus completes expansion for DEET insect repellent; Linde to build air-separation unit in Malaysia; Startup of new purified terephthalic acid line in China; Praxair signs contracts with glassmaker; and more 16 Newsfront New Developments Take Shape for U.S. Petroleum Refiners Process safety strategies, water use and alkylation were among the topics figuring prominently at the 2016 AFPM meeting 22 Newsfront Protecting Your Industrial Control System A holistic and proactive approach to cybersecurity can help protect your industrial control system from hackers Technical and Practical 38 Facts at your Fingertips Insulating Heat-Transfer Fluid Piping This one-page reference provides information about insulation used for heat-transer fluid systems 40 Technology Profile Styrene-Butadiene Rubber via an Emulsion Process This column describes a process for making styrene-butadiene rubber using an emulsion-based approach 58 Feature Report Part 1 Equipment Reliability Trends of Top Performers in the CPI Focusing on a " reliability culture, " mechanical availability and optimum costs leads to top performance 65 Feature Report Part 2 Integrated Risk-Management Matrices An overview of the tools available to reliability professionals for making their organization the best-in-class ChemiCal engineering www.Chemengonline.Com may 2016 1 16 65 50 42 Volume 123 | no. 5http://www.chemengonline.com http://www.Chemengonline.Com