APR Nov/Dec 2022 - 80

EDITOR'S
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Inhaler Test Equipment
The Volume and Resistance Compensator
(VRC) is designed for those pioneering the
integration of abbreviated impactor measurements
(AIM) into established workflows
to streamline inhaler testing. For all orally inhaled
products (OIPs), full resolution cascade
impaction is a compendial method used to
measure aerodynamic particle size distribution
(APSD). AIM, in combination with Efficient
Data Analysis (EDA), has potential to reduce
the time and cost of such measurements, but
comparability with full resolution measurements
is important and not yet assured. The
new VRC directly addresses this issue and is especially
relevant for the testing of dry powder
inhalers (DPIs). The VRC provides a robust easyto-use
tool that allows users to refine flow rate
rise time profiles for AIM apparatus to ensure
comparable conditions for aerosol generation
allows volume and flow resistance to be independently
varied is suitable for all types of AIM
apparatus with successful matching demonstrated
for both the Next Generation Impactor
(NGI) and Andersen Cascade Impactor (ACI)
and their AIM counterparts.
Copley Scientific
www.copleyscientific.com
Cell Line Development Kit
The Gibco™ Freedom™ ExpiCHO-S™ Cell Line
Development Kit allows users to generate cell
lines suitable for clinical development without
their own starter cells, vectors or prior experience
in the field. The new kit uses Thermo
Fisher's ExpiCHO-S cell line and a new powerful
media platform specifically developed for
it. The kit is based on a novel set of ProBioGen
vectors equipped with strong promoters, selection
markers and protective elements providing
expression stability. Together with a
simple workflow optimized by ProBioGen, the
kit provides short development time, reproducibly
high titers (3-5 g/L) and high expression
stability.
ProBioGen
www.probiogen.de
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| November/December 2022
TOP|TECH
Tangential Flow Filtration
Purification System
The OptiMaxx tangential flow filtration (TFF)
system, with four different sizes in the product
line, ensures dynamic separation control
in all applications and can be customized to
the end-user's unique needs through its exclusive
open architecture. With the ability to
run two different pumps and two different
flow rates simultaneously, OptiMaxx is truly
configurable to meet the end user's TFF processing
needs. Additional features include
a customizable recipe configurator, an intuitive
HMI touchscreen, and many filtration
control schemes. The system allows users to
configure process automation using multiple,
pre-programmed ultrafiltration/diafiltration
(UF/DF) phases, such as concentration,
flush, and recovery, among many others.
Furthermore, the open architecture enables
users to choose from a variety of flow paths,
filters and sensors, such as pressure, flow,
temperature or conductivity.
High Purity New England
www.hp-ne.com
Fully Automated Sample
Preparation System
The new EXTREVA ASE Accelerated Solvent
Extractor automatically extracts and concentrates
analytes of interest from solid and
semi-solid samples, such as persistent organic
pollutants (POPs), polycyclic aromatic hydrocarbons
(PAHs) or pesticides, in a single instrument,
eliminating manual sample transfer for
a walk-away sample-to-vial workflow. The system
can also perform four sample extractions
and concentrations in parallel, significantly
improving sample throughput and laboratory
productivity. With manual intervention
significantly reduced by a factor of three, in
some cases, results can be more accurate and
reliable-allowing users more time to focus on
value-added tasks. Analytical labs extracting
from solid or semi-solid matrices can pair the
sample prep instrument with gas chromatography
(GC), GC-mass spectrometry (MS) or liquid
chromatography (LC)-MS systems.
Thermo Fisher Scientific
www.thermofisher.com/extreva
»
http://www.hp-ne.com http://www.copleyscientific.com http://www.probiogen.de http://www.thermofisher.com/extreva
APR Nov/Dec 2022

Table of Contents for the Digital Edition of APR Nov/Dec 2022
