APR Nov/Dec 2022 - 82

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SECTION TITLE
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Pharmaceutical
P.I.N.
Points
Patent Innovation News
Article Title
The purpose of this column is to highlight
and summarize recent key patents in the
pharmaceutical arena issued by the US
Patent Office in September-October, 2022.
Neelam Sharma, MS,
LakshmiLavanya Kundurthy, BE and
Hemant N. Joshi, Ph.D., MBA*
Tara Innovations, LLC
www.tarainnovations.com and www.tara-marketing.com
*hemantjoshi@tarainnovations.com
Introduction
Paragrapgh Text
Ultrasonic Urinary Bladder
Drug Delivery;
A. Geva and L. Kushkuley; Vensica Medical
Ltd, Tel Aviv, Israel; U.S. Patent # 11478618;
October 25, 2022.
The present invention relates to the field of intravesical therapy.
Intravesical treatment is a method that allows direct transfer of
drugs into the urinary bladder. It may involve several challenges and
limitations such as non-effective penetration of therapeutic drug
delivery to the bladder. The current invention is a kit comprising a
urinary catheter with a first and a second longitudinal lumen. The
first longitudinal lumen is disposed inside a balloon and configured
to inflate the balloon. The second longitudinal lumen is disposed
outside the balloon and configured to deliver a therapeutic fluid into
the urinary bladder. Activation of one ultrasonic transducer in the
urinary bladder causes cavitation bubbles to form in the therapeutic
fluid adjacent to an internal surface of the urinary bladder, and little
or no cavitation bubbles are formed in acoustic coupling medium.
Author Name
Author Title
Author Company
Device and Methods for
Endoscopic Patch Delivery;
A. Smith, A. Pic, and H. Rebar;
Boston Scientific Scimed, Maple
Grove, MN; U.S. Patent # 11,439,374;
September 13, 2022.
Endoscopic procedures are performed for various reasons
including - collection of tissue samples, mucosal resection
and submucosal dissection. Such procedures can lead to
wounds in need of repair. This patent claims a method of
delivering a patch to the target site. It involves a patch in
folded or crimped configuration, releasing the patch from
the endoscope to the target site. The patch is at the distal
end of the endoscope on a cap secured by a flexible band.
Releasing the patch from the cap includes actuating a
wire to cut the flexible band from the cap. The patch may
comprise of a biomaterial such as chitosan or extracellular
matrix and may be biocompatible and/or bioresorbable.
Adjustable Dosing Delivery and
Multi-Sectioned Drug Compartment;
D. Shahaf and I. Shichor; Sipnose Ltd.,
Israel; U.S. Patent # 11,471,618;
October 18, 2022.
The present invention pertains to a system for delivering aerosolized
substance to a natural orifice of the body. In the pharmaceutical and
therapeutic areas, although nasal delivery is an acceptable delivery
route, providing an adjustable dose to a specific need is always an
obstacle. It is therefore needed to provide a system which can be
optimized for efficient delivery of a substance to a target site. This
device is for delivering a predetermined volume of at least one
substance within a body cavity of a subject. The device contains a)
a capsule for containing the predetermined volume of substances;
b) a delivery end, having at least one orifice of diameter D, c) a valve
mechanically connectable to the capsule- an active configuration
and an inactive configuration; d) a fluid tight chamber. The capsule
further contains at least one mixing mechanism that mixes the
substances and the pressurized gas after the valve is reconfigured
to the active configuration.
82 |
| November/December 2021
ember 2022
http://www.tarainnovations.com http://www.tara-marketing.com
APR Nov/Dec 2022

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