eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 18

FP Assays-Therapeutic Targets
Cat number
Product
50293
78111
78107
79859
78355
60400
72020
79899
78317
60350
HSP90α N-terminal Domain Assay Kit
JAK2 JH2 Pseudokinase Domain inhibitor Screening Assay Kit
TYK2 JH2 Pseudokinase Domain Inhibitor Screening Assay Kit
KRAS(G12C) Nucleotide Exchange Assay Kit
KRAS(G12D) Nucleotide Exchange Assay Kit
PDE10A Assay Kit
KEAP-Nrf2 Inhibitor Screening Assay Kit
Cereblon Binding Assay Kit
PARPtrap™ Combo Assay Kit for PARP1 and PARP2
PDE5A1 Assay Kit
Size
96 reactions
384 reactions
384 reactions
384 reactions
384 reactions
96 reactions
96 reactions
96 reactions
384 reactions
96 reactions
Conclusion
BPS Bioscience offers validated FP-based assay kits,
saving scientists time and money by eliminating
the need for many steps of optimization such as
experimental design, labeling and validation of
the fluorescent tracer, or buffer composition. Our
kits contain high-quality purified proteins and are
provided with a validated protocol.
References
1. Jameson DM, Croney JC. Fluorescence polarization:
past, present and future. Comb Chem High Throughput
Screen. (2003) 6(3): 167-173. PMID: 12678695. https://
pubmed.ncbi.nlm.nih.gov/12678695/
2. Hendrickson OD, Taranova NA, Zherdev AV, Dzantiev
BB, Eremin SA. Fluorescence Polarization-Based
Bioassays: New Horizons. Sensors (2020) 20(24): 7132.
PMID: 33322750. https://pubmed.ncbi.nlm.nih.
gov/33322750/
3. Moerke NJ. Fluorescence Polarization (FP) Assays for
Monitoring Peptide-Protein or Nucleic Acid-Protein
Binding. Curr Protoc Chem Biol. (2009) 1(1): 1-15.
PMID: 23839960. https://pubmed.ncbi.nlm.nih.
gov/23839960/
4. Kido C, Murano S, Tsuruoka M. Rapid and simple
detection of PCR product DNA: a comparison
between Southern hybridization and fluorescence
polarization analysis. Gene (2000) 259(1-2): 123-127.
PMID: 11163969. https://pubmed.ncbi.nlm.nih.
gov/11163969/
5. Luk KC, Hyde EG, Trojanowski JQ, Lee VM. Sensitive
fluorescence polarization technique for rapid
screening of alpha-synuclein oligomerization/
fibrillization inhibitors. Biochemistry (2007) 46(44):
12522-12529. PMID: 17927212. https://pubmed.ncbi.
nlm.nih.gov/17927212/
6. Nihel T, Mendelson RA, Botts J. The site of force
generation in muscle contraction as deduced from
fluorescence polarization studies. Proc Natl Acad Sci
U S A. (1974) 71(2): 274-277. PMID: 4521799. https://
pubmed.ncbi.nlm.nih.gov/4521799/
18

https://pubmed.ncbi.nlm.nih.gov/23839960/ https://pubmed.ncbi.nlm.nih.gov/23839960/ https://pubmed.ncbi.nlm.nih.gov/11163969/ https://pubmed.ncbi.nlm.nih.gov/11163969/ https://pubmed.ncbi.nlm.nih.gov/12678695/ https://pubmed.ncbi.nlm.nih.gov/17927212/ https://pubmed.ncbi.nlm.nih.gov/12678695/ https://pubmed.ncbi.nlm.nih.gov/17927212/ https://pubmed.ncbi.nlm.nih.gov/33322750/ https://pubmed.ncbi.nlm.nih.gov/4521799/ https://pubmed.ncbi.nlm.nih.gov/33322750/ https://pubmed.ncbi.nlm.nih.gov/4521799/

eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development

Table of Contents for the Digital Edition of eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development

eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 1
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 2
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 3
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 4
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 5
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 6
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 7
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 8
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 9
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 10
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 11
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 12
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 13
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 14
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 15
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 16
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 17
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 18
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 19
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 20
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 21
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 22
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 23
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 24
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 25
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 26
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 27
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 28
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 29
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 30
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 31
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 32
eBook: Biochemical and Cell-Based Assays for Targeted Cancer Drug Discovery and Development - 33
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