MJBizMag July 2022 - 85
MJBizDaily Buyers Guide Extraction
mjbizdaily.com
DIFFERENCES WHEN EXTRACTING
PSILOCYBIN
MJBizDaily reports that the global market for
therapeutic psychedelics (including substances
such as LSD and ketamine) is projected to be
worth $6.8 billion by 2027.
Ambitious entrepreneurs, however, should
understand the differences between the
mushroom and cannabis extraction processes.
According to Moss, the molecular makeup of a
substance like psilocybin is the total opposite of
marijuana and hemp plants.
" Cannabinoids are non-polar molecules
that exist in very high concentrations in the
raw material itself, " Moss says, adding that
cannabinoids make up about 15% of the
dry weight of cannabis. " On the other hand,
psilocybin (and related tryptamines) are watersoluble
polar molecules that exist in relatively
low concentrations, " less than 2% of the dry
weight of the mushroom.
Since extracting water-soluble compounds is different than extracting non-polar molecules, much
of the extraction equipment used by cannabis manufacturers would not be adequate to extract
psilocybin, he says.
Moss adds, " The methodologies and techniques used when dealing with aqueous chemistry are
vastly different from their non-polar counterparts. Techniques like sub- and supercritical CO2
hydrocarbon extraction are not going to work here. "
OUTFITTING A FACILITY TO EXTRACT FOR PSILOCYBIN
Even the most experienced professionals would find it challenging to utilize the equipment and
methods meant for cannabis extraction on psilocybin.
" Much of the off-the-shelf equipment that was designed specifically for cannabis and extraction
and post-processing will not serve a purpose in psilocybin extraction, " Moss explains.
Despite this, cannabis-extraction facilities can outfit or renovate their spaces for psychedelic
extraction.
" The facility construction, explosion-proofing and solvent-handling capabilities will be useful tools
for making the switch, " Moss adds. " Many of the tools, tanks, pumps and general equipment will
help an individual who knows their chemistry well and has a process designed for its use. "
" For those who have only experience in extraction of cannabinoids, " Moss says he " would look to
other extraction industries for guidance, as the similarities between psilocybin and cannabis are
few and far between. "
and
Ryan Moss
25
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MJBizMag July 2022
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