October/November 2020 - 32

Therapy
Q&A WITH ORTHOPEDIST
DR. ALLAN MISHRA
Current Innovations with Stem Cells & Platelet-Rich Plasma
By Nick Friar
Contributing Writer
W
..hen it comes to innovative treatment options,
..Platelet-Rich Plasma (PRP) and stem cell
..therapy comes up a lot. But what is the level
of understanding of these regenerative medicine among
the average person? The goal of regenerative medicine is
to stimulate the body to heal itself, utilizing the person's
natural healing abilities. To understand PRP vs stem cell
treatments, you need to know more about the science
behind each.
Dr. Allan Mishra is an orthopedist who specializes in
sports medicine for the Menlo Medical Clinic in Menlo Park,
CA, which is part of the Stanford Health Care system.
He also conducted the first PRP injection study on
tennis elbow in 2006, and he remains a prominent voice
in the advancement of PRP injections in sports medicine.
Dr. Mishra spoke with Training & Conditioning about
the advancements of PRP injections, how those differ
from stem cell injections, and how he recommends the
30 | Training & Conditioning | October/November 2020
procedure to patients.
Training & Conditioning: You've seen the development
of PRP injections from the ground up. What are some of
the changes with PRP over the years that have made this
come to the forefront, where we now see big-time athletes
turning towards this option depending on the injury?
Dr. Allan Mishra: Ten, 15 years ago, using a component
of your own blood to treat a tendon or a ligament injury
or knee osteoarthritis or degenerative disc disease, I
think, was considered flat out crazy. I know that when I
first started doing it, people were highly skeptical - and
appropriately so, because there was no data to support the
use of PRP or stem cells as preparations for a variety of
different athletic or sports medicine disorders.
So, I went about it as scientifically as I possibly could.
We did, initially, a pilot study - a small number of patients,
but controlled - and found that using your own blood in
the form of Platelet-Rich Plasma was effective in a small

October/November 2020

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