Pharmaceutical Technology Europe - August 2012 - (Page 13)

TOP TECHNOLOGIES Biocontainers Suitable for both R&D and production purposes, Meissner’s TepoFlex biocontainers offer high fluid integrity performance in both 2D- and 3D-configurations in volumes from 50 mL to 1000 L. The containers can be used with the company’s BioFlex tubing assemblies to provide secure fluid transfer flexibility, which can include capsule filters for prefiltration through sterile filtration requirements. Fully deployed biocontainers can also be used with the FlexStation rigid outer containers to provide integral fluid management options. Meissner Filtration Products www.meissner.com Single-Use Filling System Flexicon Liquid Technology offers its asepticsu single-use fluid technology for peristaltic precision filling. Changeovers between batches can take place within minutes and once the filling process is complete, the system can be easily removed from the filling line, making it particularly suitable for small-batch production. The technology uses the company’s Accusil platinum-cored silicon tubing and provides filling accuracy of ±0.5%. A variety of different fluid path options are available. Flexicon Liquid Filling, part of the Watson Marlow group www.wmpg.co.uk Tangential Flow Filtration Pall’s single-use Tangential Flow Filtration (TFF) system is part of the company’s Allegro range. Combining the advantages of single-use manifolds with an engineered automated design, the system provides control of key parameters and ease-of-use in manufacture. The system has 1/2-inch tubing and a feed pump capacity of 1000 L/h. It can be run with a 20 L or 100 L feed biocontainer and run in fed batch mode for processing larger volumes. Pall Life Sciences www.pall.com Freeze Dryer Telstar has extended its range of freeze dryers with a unit suited to clinical and small production scale batches. The Lyotris system has a 1 m2 loading surface and capacity for approximately 1600 10R-type vials or 30 L of bulk product. The standard version includes the components required for automatic cleaning and steam sterilisation processes and filter integrity testing. Telstar www.telstar.eu 2 Enhancing Bioavailability 10 German Pricing 5 Nanoparticle Engineering 11 Blogs 7 News and Twitter Trends 13 Top Technologies 9 Peer Reviewed Research 14 Staff http://www.wmpg.co.uk http://www.meissner.com http://www.telstar.eu http://www.pall.com

Table of Contents for the Digital Edition of Pharmaceutical Technology Europe - August 2012

Pharmaceutical Technology Europe - August 2012
Bioavailability Enhancement: When to use Hot-Melt Extrusion Versus Spray Drying
Tackling Solubility Issues with Nanoparticle Engineering
News Bites and Trends on Twitter
Peer-Reviewed Research: Carbon Measurement Methods for Cleaning Validation
Changing German Market Depresses the Pharma Industry
Blogs: Big data; the Olympics and GSK; FDA lawsuit; and unlicensed medicines
Top Technologies: Biopharmaceutical Equipment

Pharmaceutical Technology Europe - August 2012