The Column - March 2008 - (Page 6)

News The Column www.thecolumn.eu.com March 2008 News Study to develop anti-addiction therapies Scientists at the Open Mind Institute (OMI), Slovenia, are studying the effects of medicinal plants to develop a better understanding of anti-addiction therapies. Researchers in the OMI — an experimental research and development institute — are evaluating iboga, from which the anti-addictive compound ibogaine is derived as an anti-addictive cure. The study is using Syngene’s software Dymension for the analysis of 2D protein gels to determine the ibogaine’s effects. Working in collaboration with scientists at the University of Ljubljana, Slovenia, the scientists are using Dymension to determine any post ibogaine treatment differences in silver stained rat brain proteins run on 2D gels. The protein profiles are used to establish which proteins are up- or down-regulated. The research could lead to a better understanding of the pharmacodynamics of anti-addiction therapies and Dr Roman Paskulin, director of the OMI, commented, “We are relatively new to proteomic analysis so we chose to install Dymension software because we want to rapidly perform complicated analysis.” “Using Dymension to analyse our 2D gel images in association with MALDI-TOF on the resulting protein spots, we have seen increases in four metabolic enzymes after ibogaine treatment and are now looking at the significance of these findings,” added Paskulin. Syngene’s divisional manager Laura Sullivan said, “We are delighted to see our Dymension software being used to accelerate the pace of such interesting research.” For more information visit Syngene’s website at www.2dymension.com or the Open Mind Institute’s website at www.omi.si 2008 Olympic Games illegal substance tests Agilent Technologies has hosted a delegation from China’s Anti-Doping Agency ahead of the 2008 Olympic Games. The meeting, the first of three leadership delegations, included technical training on anti-doping instruments and methods developed by Agilent. The China Anti-Doping Agency is one of the largest and most technically advanced testing facilities in the world. It will examine more than 4500 samples from athletes during the Olympic Games being held in China this summer. The Agency’s Beijing-based laboratory has been equipped with state-of-the-art Agilent liquid chromatography (LC), gas chromatography (GC) and mass spectrometry (MS) instruments to confirm the chemical identity of suspected banned substances found in testing samples. “China has quickly become a world model for anti-doping efforts. Agilent’s liquid chromatography and mass spectrometry instrumentation will help make China’s Anti-Doping Agency testing in the 2008 Olympic Games the most technologically advanced yet,” commented Du Lijun, director of China’s Anti-Doping Agency. “We are proud of our relationship with China’s anti-doping efforts, which date back to the 1980s,” said Mike McMullen, vice president and general manager of Agilent’s Chemical Analysis Solutions Unit. The China Anti-Doping Ageny, which was previously known as the China Doping Control Center is located in the National Olympic Center, a main venue for the 2008 Olympic Games. For more information visit Aglient’s website at www.agilent.com www.agilent.com Links: 6 www.2dymension.com www.omi.si http://www.thecolumn.eu.com http://www.2dymension.com http://www.omi.si http://www.agilent.com http://www.2dymension.com http://www.agilent.com http://www.omi.si

Table of Contents for the Digital Edition of The Column - March 2008

The Column - March 2008
Contents
News
Zosimus - Never Mind the Selectivity - Look at the Plate Count!
HPLC Analysis of Lysozyme in Different Types of Wine
Market Trends & Analysis
A Holistic Approach to Increasing Analytical Throughput on a Modern Gas Chromatograph
If It's Broke, Fix It - Q&A
The Applications Book
LC World Talk - Shimadzu's Newsletter for the HPLC Global Community
LC World Talk Contents
Applications of Ultra Fast HPLC
The World's Most Advanced Liquid Chromatograph
2D-HPLC for Bioanalysis "Co-Sense for BA" System
Metabolite Identification Software

The Column - March 2008