The Column - November 2006 - (Page 6)

News The Column www.thecolumn.eu.com November 2006 NewsAgilent on the Atlas over three years to the Cancer Genome The National Cancer Institute NCI has Characterization Centers CGCC that announced grant recipients for its are designed to implement the Atlas Cancer Genome Atlas pilot project. project. As a part of the NCI Included in the recipients were initiative, each CGCC is expected three institutions using microarray to process a minimum of 1000 platforms from Agilent clinical samples per year. Technologies. All three institutions will rely The University of North on Agilent's genomics solution, Carolina, Dana-Farber Cancer comprising microarrays, reagents, Institute and Memorial hardware and data analysis tools. Sloan-Kettering Cancer Center For more information visit the were among seven that were company's website at awarded a combined $35 million in www.chem.agilent.com grants. The money will be spread Shimadzu's MS for biomarker characterization relatively large amounts so it is easy to Researchers from Middlesex University, UK obtain samples from patients and analyse are using a Shimadzu MALDI-TOF mass the molecule's degree of spectrometer to characterize new hyperglycosylation. He added, Our biomarkers that predict for Down's preliminary work has shown that the syndrome. molecules have different glycosylation The instrument will be used to patterns for various diseases and we are analyse the association of now running thousands of urine samples hyperglycosylated human chorionic through the MALDI-TOF system to look at gonadotrophin hCG hormone with the spectral patterns. We hope to find diseases. A heavily glycosylated specific structural alterations of the hCG fragment of hCG has been shown to molecules associated with certain be produced by malignant tumours and conditions, such as Down's Syndrome has been observed during abnormal pregnancies, as this could provide a pregnancies, such as Down's syndrome. revolutionary diagnostic test that would be Professor Ray Iles, the associate dean of very quick, easy and cheap to perform. research at the School of Health and Social For more information please visit the Sciences explained, The hCG hormone and company's website at www.shimadzu.co.uk a metabolite, hCG http://www.thecolumn.eu.com http://www.chem.agilent.com http://www.shimadzu.co.uk http://www.chem.agilent.com http://www.shimadzu.co.uk

Table of Contents for the Digital Edition of The Column - November 2006

Contents
News
Opinion
Market Trends & Analysis
The Low Down on Light-Scattering Detection
Old Questions ? New Solutions: Modern Ways for Complex Polymer Analysis and Additive Tracing
Supplies and Services
Country Focus
Q&A

The Column - November 2006

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