The National 2022 Sponsors Diamond Platinum Gold Bronze Silver Crystal Teamwork makes the debridement work When you combine your sharp debriding skills with the ongoing debridement power of SANTYL Ointment, you can remove necrotic tissue at the macroscopic and microscopic levels without harming healthy granulation tissue. It's all about giving your patients a clearer path to closure.1 Pewter Copper More than half of all patients pay $10 or less for their SANTYL Ointment prescriptions.2 Reduction in ulcer area1 from baseline at 6 weeks 36% Sharp debridement + supportive care* (p=ns)†‡ 68% SANTYL Ointment + sharp debridement + supportive care* (p<0.001)† See the evidence *Supportive care in the SANTYL Ointment group included ALLEVYN◊ Foam Dressing, cast padding and Coban™ †All patients agreed to wear an offloading boot or other appropriate device. ‡Supportive care in the control group was the clinician's choice. 46 Important Safety Information Indications: Collagenase SANTYL Ointment ( " SANTYL " ) is a prescription-only medication indicated for debriding chronic dermal ulcers and severely burned areas. Contraindications: SANTYL is contraindicated in patients who have shown local or systemic hypersensitivity to collagenase. Warning and Precautions: The optimal pH range of collagenase is 6 to 8. Higher or lower pH conditions will decrease the enzyme's activity and appropriate precautions should be taken. The enzymatic activity is also adversely affected by certain detergents, and heavy metal ions such as mercury and silver which are used in some antiseptics. As such, the wound should be properly cleansed prior to application of SANTYL. Debilitated patients should be closely monitored for systemic bacterial infections because of the theoretical possibility that debriding enzymes may increase the risk of bacteremia. A slight transient erythema has been noted occasionally in the surrounding tissue, particularly when SANTYL was not confined to the wound. SANTYL is not indicated for wound closure. Discontinue use of SANTYL after granulation tissue is well-established. Adverse Reactions: No allergic sensitivity or toxic reactions have been noted in clinical use when used as directed. The risk information provided herein is not comprehensive. For complete prescribing information, please refer to the accompanying PI or visit: https://santyl.com/sites/default/files/2019-12/SANTYL-PI.pdf. You are encouraged to report negative side effects of prescription drugs to FDA. Visit MedWatch or call 1-800-FDA-1088. apmanews JULY/AUGUST 2022 List is current as of June 30, 2022. bandages.