eBook: TOC and Microbial Detection Monitoring - 15

Continuous TOC Monitoring for Real-time Release

With real-time sensor status data available at any time,
the process can run more efficiently and critical measurement loops can be monitored for potential faults. ISM
technology helps to identify when routine maintenance is
required, significantly reducing the risk of unscheduled
downtime. Each of these diagnostic monitors is accessible
through simple service menus, allowing the user to
immediately assess the maintenance needs of the instrument
without having to review the local service archive data.
Conclusion
Global pharmaceutical requirements present an array of
regulations that need to be assessed by pharmaceutical
manufacturers when designing and validating a process
control and monitoring system. By approaching the
regulations in a structured, hierarchical method, a concise
list of applicable regulatory requirements can be compiled.
These requirements can then be expanded upon by including non-regulatory best practices aimed at aspects of
process control, which apply to the parameter being monitored and the manufacturer's specific application.

As they pertain to TOC and conductivity, regulations and
best practices commonly focus on effective process
monitoring and timely response to changes in water
system behavior. These objectives are most reliably met
by a continuous, real-time measurement system equipped
with advanced features which allow the user to quickly
assess the behavior and health of the water system.
The advanced design and sensor diagnostics of the
6000TOCi provide simple and intuitive system dashboards to quickly assess the health of both the water
system and the instrumentation. The efficient engineering design of the sensor also eliminates complex
mechanical components which are common points of
failure in other TOC sensor designs, resulting in a highly
robust and reliable instrument. Combined with the
versatile M800 Transmitter, the 6000TOCi Total Organic
Carbon Sensor from METTLER TOLEDO Thornton, delivers
an effective, robust, reliable and compliant TOC measurement solution designed for the real-time release of bulk
pharmaceutical waters.
www.mt.com/6000TOCi

www.mt.com/thornton
For more information

METTLER TOLEDO Group
Process Analytics Division
Local contact: www.mt.com/pro-MOs

Subject to technical changes
ISM and UniCond are registered trademarks of the METTLER TOLEDO Group.
©07/2018 METTLER TOLEDO. All rights reserved
58 087 194 Rev B 07/18

http://www.mt.com/6000TOCi

eBook: TOC and Microbial Detection Monitoring

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