eBook: TOC and Microbial Detection Monitoring - 21

Conductivity Measurement of Water

Ensure Pharmacopeia Compliance
with Digital Conductivity Sensors
The conductivity limits of pharmaceutical bulk waters must meet the requirements of the applicable
global pharmacopeia. Further, the conductivity instrument itself must comply with calibration
requirements to meet all global pharmacopeias. UniCond® sensors not only confirm compliance,
they also provide the highest degree of accuracy.

The need for better performance
As requirements for pharma waters
become ever stricter, so the need for
increased analytical measurement
accuracy and repeatability has become greater.
The advent of the digital sensor has
opened up new horizons for the performance of in-line analytical equipment, and provides benefits in ease of
use that non-digital sensors cannot
match.

ceived at the readout instrument is
therefore always assured.

Major improvement in accuracy
Signal degradation and variance is
eliminated with UniCond sensors because of the integrated measurement
circuit. Impedance and capacitance
problems associated with analog sensors and cable length are eradicated.
Further, integrating the sensor and the
measuring circuit provides far greater
measurement accuracy compared
with analog probes.

Digital signal is extremely robust
Traditional analog conductivity measurement systems can be prone to
signal loss between sensor and transmitter due to interference to the AC
signal.
UniCond sensors operate differently.
Signal processing takes place within
the probe head itself. Measurements
are then sent digitally to the transmitter. Digitizing the analog signal in
proximity to the sensing element is a
significant improvement, as the robust
signal is immune to interference or
degradation. High confidence in the
reliability of the measurements re-

METTLER TOLEDO Pharmaceutical Waters

Error-free start up
A reliable and accurate digital signal
is not the only benefit of UniCond sensors. Intelligent Sensor Management
(ISM®) technology means on-board
memory stores and communicates
complete sensor identification and
calibration data to the readout instrument for simplified startup and calibration. The result is convenient Plug and
Measure functionality, and greatly reduced chances of operator error.
With conventional sensors, the user
must remember to manually enter the
precise cell constant and temperature
calibration data for each individual

probe into the transmitterʼs memory
to achieve rated accuracy. The
UniCondʼs integral sensor eliminates
questions about which cell constant to
use, calibration data to enter, spare
parts to maintain and other decisions
where multiple sensor types would
normally be required. This significantly
improves system simplicity and
reliability.

UniCond for USP compliance
Compliance with USP < 645 >, EP
2.2.44 and all other global pharmacopeias requires calibration of the sensor
cell constant, the measurement circuit,
and the transmitter. The measurement
circuit in UniCond sensors is traceable
to NIST and is calibrated prior to assembly. The cell constant is traceable
to ASTM. In addition, UniCond sensors
can be calibrated in-line, as recommended by the USP and EP. Also, ISM
simplifies regulatory compliance by
storing sensor calibration data internally and reducing written record
keeping.
Download the Conductivity Theory
guide:
c www.mt.com/pro-pharma-con-

ductivity

http://www.mt.com/pro-pharma-con-ductivity http://www.mt.com/pro-pharma-con-ductivity

eBook: TOC and Microbial Detection Monitoring

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