Children's Hospitals Today - Fall 2023 - 16

FEATURE / RESEARCH
EXPANDING THE HORIZON
Children's hospitals are always leading, conducting and publishing research to
advance children's health. For example, Rady Children's Hospital is currently
involved in more than 890 research studies by some 230 investigators, including
200 active clinical trials. While the discoveries and developments from children's
hospitals are innumerable, here are five examples of new insights that affect the
lives of children and may lead to new ways to treat or cure patients.
ALS
Researchers at Boston
Children's Hospital have
identified proteins involved
in the innate immune system
that could be at the root of
neurodegenerative conditions
such as amyotrophic lateral
sclerosis (ALS), opening
the door to new potential
pathologies to target.
SEIZURES
Research from Cook Children's
Health Care System could help
precisely identify the parts of
the brain that cause seizures
in children with epilepsy,
resulting in safer and more
effective treatments.
MRSA
Methicillin-resistant
Staphylococcus aureus
(MRSA) is associated with
high morbidity and mortality.
Children's Hospital New Orleans
developed an inexpensive nasal
decolonization regimen that
decreased MRSA rates by 50%.
PEANUT ALLERGY
Children's Hospital Colorado
developed a skin patch that
was shown to be effective
in desensitizing children to
peanuts and increasing the
peanut dose that triggered
allergic symptoms.
GENOMICS
Researchers at Rady Children's
Institute for Genomic Medicine
estimate that screening
every baby born in the U.S. for
genetic disorders would save
15,000 lives annually. Rady
Children's has sequenced
the DNA of more than 7,500
people, and researchers at
Stanford Medicine sequenced
and diagnosed a genetic
disease in less than eight
hours, a world record.
16
CHILDREN'S HOSPITALS TODAY Fall 2023

Children's Hospitals Today - Fall 2023

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