Origene_Jan2021_ProperAntibodyDesignKeeps - 5

Proper Antibody Design Keeps Specificity In Mind

UltraMAB is a subset of TrueMAB that has gone
through rigorous specificity testing: a hybridization
test using a microarray chip of 17,000 proteins. Those
antibodies that are proven to bind only to their
intended target and nothing else can be qualified for
UltraMAB.
Thanks to advanced biomedical engineering,
scientists can swiftly create designer antibodies
with desired features. When the COVID-19
pandemic started, scientists quickly generated
human antibodies specific for the virus spike
protein-which binds to ACE2 and initiates viral
entry into the host cells. Such antibodies can be
used to neutralize the virus and serve as a potential
treatment option. Moreover, researchers can even
create antibody-like proteins that don't exist in
nature, such as bi-specific antibodies often used as
cancer therapeutics.
In this ebook, you will read about the fascinating
ways bioengineering has changed how antibody
molecules are applied to research and the clinical
world. Despite all the changes, specificity remains
the core value determinant of an antibody, albeit
naturally or recombinantly made.

GENengnews.com

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Origene_Jan2021_ProperAntibodyDesignKeeps

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