Agilent - Breakthroughs in Immunotherapy- 2019 - 23

Breakthroughs in Immunotherapy

business. "Our goal is to bring the best possible performance
and experience to the benchtop. We will know we have
succeeded when you get the same answer, again and again,
no matter who is operating the cytometer."
As inferred by Dr. Wang , the resolution wars in cytometry
are drawing to a close. Fluorescence resolution in most
instruments is comparable and sufficient. The competition
is, therefore, rightfully shifting to usability features that are
dramatically improving accessibility, efficiency, and decision
making. Many experts in the field predict software experience and automation to be the top differentiators among
cytometers going forward, especially at the bench, where
everyone wants them to be.
As a cell engineering tool, flow cytometry is employed
from screening through validation of accurate targeting
to comprehensive phenotypic characterization. A great
example is Precision BioSciences. This company is applying
its ARCUS genome editing technology to develop allogeneic
cell-based immunotherapies. Their immunotherapies are
derived from select, healthy subjects as opposed to compromised cancer patients to overcome inherent problems
of consistent and scalable manufacturing of autologous
cells. "Cytometry is the key tool in our work. This is how
we analyze our cells before, during and after the manufacturing, including how we trace our cells in patients and
analyze the cellular component of their immune system
during treatment", explained Vladimir Senyukov, the Director
23

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NovoCyte Advantages
Wider dynamic range for detecting leads
to a reduction in time and mistakes
Accurate volumetric-based,
direct cell counting system
NovoExpress drag-and
drop function, makes data
analysis quick and efficient
NovoExpress can generate
PDF reports with one click
Innovative fluidics deliver
higher reproducibility and
exceptionally low CV's
Fully automated wash and shut
down; ready-to-go for the next user
Walk-away automation
can be achieved with the
NovoSampler Q™

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Agilent - Breakthroughs in Immunotherapy- 2019

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