Clinical OMICs - Issue 2 - (Page 3)

Innovative Practices, Actionable Results Molecular diagnostics is entering a critical phase-will the benefits outweigh the costs of deploying the new technologies? CANCER OMICS-HOW MUCH INFORMATION IS ENOUGH . . . . 8 Multiple tests are now either available or under development that aim to help clinicians and patients make better decisions about treatment. PATHOLOGISTS EMERGE FROM THE LAB . . . . . . . . . . . . . . . . . . . . .12 New technologies will help bring disease specialists closer to patients. Regular Features INNOVATOR . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .15 THE SCHADT EQUATION Eric Schadt, professor of genomics at Icahn School of Medicine at Mount Sinai, uses mathematical techniques developed for Wall Street to determine which patients require treatment and then specify the best treatment for them. SNAPSHOT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .19 FDA AND LDTS- WHAT'S NEXT The Administration is claiming power over laboratory-developed tests and increasingly flexing its muscles. CASE STUDY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .22 HIGH-SENSITIVITY DETECTION OF CANCER BIOMARKERS Somatic mutation PCR test suppresses amplification of wild-type template DNA, and selectively amplifies mutant templates. NEWS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 BEST OF THE WEB . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27 NEW PRODUCTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .28 www.clinicalomics.com April 30, 2014 Clinical OMICs 3 https://www.youtube.com/channel/UCXBPPWZv--Ne4NfAUHcc8hg https://twitter.com/ClinicalOMICs http://www.clinicalomics.com

Table of Contents for the Digital Edition of Clinical OMICs - Issue 2

Table of Contents

Clinical OMICs - Issue 2