Clinical OMICs - Issue 8 - (Page 3)

Innovative Practices, Actionable Results From checking isolated hotspots to surveying whole exomes and even whole genomes, sequencing is getting more comprehensive -and clinically relevant. NGS READY FOR CLINICAL ONCOLOGY TESTING . . . . . . . . . . . . . . 7 Sequencing technology can assess the oncogenome, not just a few hotspots, to determine cancer predisposition. THE PUBLIC HEALTH ROLE IN TRANSLATING ADVANCES IN GENOMICS . . .12 Five main areas of public health genomics are helping to improve health and prevent disease. CYTOGENOMIC ANALYSES FOR GENETIC DISEASE DETECTION AND DIAGNOSIS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .18 Tests for developmental diseases provide useful information for both clinicians and families. POINT-OF-CARE REACHES A CROSSROADS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .22 As diagnostic variety expands, so too do the challenges. Regular Features SNAPSHOT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .26 How MDx and Histology Will Deliver Growth to U.S. IVD Market Market recovery will depend on the contributions of diagnostic testing segments. CASE STUDY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .28 Droplet Digital PCR Primes Liquid Biopsies for the Clinic: Researchers investigate the use of ddPCR to noninvasively interrogate the cancer genome. NEWS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 NEW PRODUCTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .16 Cover image ©Anchan_uk-Deposit Photos Above ©Alex Raths-Deposit Photos www.clinicalomics.com BLOG ROUNDUP . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .32 August 13, 2014 Clinical OMICs 3 https://twitter.com/ClinicalOMICs https://www.youtube.com/channel/UCXBPPWZv--Ne4NfAUHcc8hg http://www.clinicalomics.com

Table of Contents for the Digital Edition of Clinical OMICs - Issue 8

Contents

Clinical OMICs - Issue 8