Clinical OMICs - Volume 2, Issue 11 - (Page 3)

Molecular Diagnostics in Personalized Medicine NGS-enabled multiplexing strategies may help drug developers and clinicians move beyond the "one biomarker/ one drug" approach to Prevail companion diagnostics. GENOMICS AIDS GESTATION OF PRENATAL MOLECULAR DIAGNOSTIC TESTS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 New approaches in genomic medicine advanced over the past several years are helping future parents eliminate the risk of common inherited genetic abnormalities. Regular Features CLINICAL GENOMICS UPDATE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 Molecularly Targeted Agents in Personalized Cancer Therapy and Diagnostics: SHIVA trial raises key questions on the efficacy of certain cancer treatments and reveals importance of genomic analysis for effective therapy. with next-generation sequencing in your clinical laboratory INNOVATOR. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 Arivale Brings Genomics to the People Wellness startup intends to democratize personalized medicine. SNAPSHOT. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 Noninvasive Prenatal Screening-Making the Case for Responsible Innovation in Genetic Testing: Growth of NIPS has launched a crusade of hope for the future of prenatal care; however, what are the limits? The Ion PGM Dx System ™ Delivering on our commitment to empower clinical laboratories to help improve patient outcomes, the Ion PGM™ Dx System enables you to develop diagnostic tests using next-generation sequencing. Validated using challenging germline variants, with library kits based on proven Ion AmpliSeq™ technology, the system enables accurate and reliable genetic analysis from more clinical samples, even with a limited amount of DNA. All with a high-level of reproducible performance you can trust, and the rapid turnaround time you need, to enable personalized care. Pursue. Pioneer. Prevail. CASE STUDY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 Innovation in Molecular Diagnostics Changes the Game in Cancer Screening: Development of a new noninvasive cancer detection technique creates potential shift in patient willingness to undergo cancer screening. Learn more at thermofisher.com/pgm-dx For In Vitro Diagnostic Use. © 2015 Thermo Fisher Scientifi c Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientifi c and its subsidiaries unless otherwise specifi ed. CO017601 0915 COMPANION DIAGNOSTICS FOR CANCER: Will NGS Play a Role?. . . 8 The rapid accumulation of new knowledge on tumor biology resulting from next-gen sequencing is forcing stakeholders to continually rethink companion diagnostics. Cover and above (top): iStock/tarmofoto Above (bottom): iStock/kirstypargeter www.clinicalomics.com NEWS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 NEW PRODUCTS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 MEETING ROUNDUP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 November 2015 Clinical OMICs 3 https://twitter.com/ClinicalOMICs https://www.youtube.com/channel/UCXBPPWZv--Ne4NfAUHcc8hg http://www.clinicalomics.com

Table of Contents for the Digital Edition of Clinical OMICs - Volume 2, Issue 11

Contents

Clinical OMICs - Volume 2, Issue 11