Clinical OMICs - Volume 3, Issue 2 - (Page 3)

Molecular Diagnostics in Personalized Medicine Blurring the distinction between "the many" and "the few," genomic science benefits not only the community, by revealing underlying causes of disease, but also the individual, by enabling personalized medicine. MEASURING THE UTILITY OF GENOMIC MEDICINE . . . . . . . . . . . 8 Evaluating the risk-to-benefit ratio of genomic health advances PROTEOMICS FOR DISEASE DETECTION AND CHARACTERIZATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .11 Bridging the gap between genotype and phenotype BIOMARKER DISCOVERY GETS A FIX ON CANCER . . . . . . . . . . . . . . . . . . . . . . . . . .16 Just because cancer is a moving target-emerging here, eluding treatment there-doesn't mean it can't be tracked. THE NEXT NEXT THING IN SEQUENCING . . . . . . . . . . . . . . . . . . . . . .21 Next-gen sequencing is preparing to navigate new molecular codescapes. Regular Features CASE STUDY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .26 Harnessing Clinically Related Big Data: The RNA-Seq Perspective: Though complex, RNA-Seq is poised to play an increasingly important role in clinical applications, and data analysis and assay design will be critical to produce consistently high-quality results and harness this developing technology's potential. SNAPSHOT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .29 Applying Genomics to Prevent Organ Rejection and Other Transplantation Complications: Applying genomics to transplantation science may reduce the need for rejection prevention therapy as well as long transplant lists. Cover: iStock / govsum NEWS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 NEW PRODUCTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .15 MEETING ROUNDUP . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .34 Above (top): iStock / ktsimage; (bottom): iStock / zmeel www.clinicalomics.com February 2016 Clinical OMICs 3 https://twitter.com/ClinicalOMICs https://www.youtube.com/channel/UCXBPPWZv--Ne4NfAUHcc8hg http://www.clinicalomics.com

Table of Contents for the Digital Edition of Clinical OMICs - Volume 3, Issue 2

Contents

Clinical OMICs - Volume 3, Issue 2