evotec_Nov23_PanOmicsDriven - 17

CELL BIOLOGY
PanOmics
High-throughput
Patient derived iPSC
Organs on a chip
Custom cell types
2D & 3D formats
High-throughput RNA-Seq
Higher throughput
proteomics
Ubiquitinomics
Acetylomics
PanHunter
Automated quality control
Adaptable for most purposes
Interactive
Data
Interpretation
Via Machine Learning / AI
Evotec's proprietary
reference database
Custom made algorithms
Expert data review and
conclusions
Customer provided compounds
Customer provided plates
Customer provided data
Customer provided questions
Plates ready for analysis
Raw Omics Data Sets
Curated and QCed data
Interpretations and Conclusions
Leading bioinformatics plat forms for interactive
multivariate data analysis
Dedicated bioinformatics experts can design
unique data analysis processes
Advanced machine learning capabilities
Data scientists to interpret large
and complex data sets
In practice, this service can be as flexible as needed
for a given project ensuring Evotec is in a unique
position to offer an end-to-end in vitro toxicology
transcriptomics service that can be customised
according to customer's needs.
The barcoded
The well ID,
The primers also
contain a barcode
sequence specific for
well identification
Following cDNA
synthesis, a final library
preparation step is
performed after pooling
of the whole plate
oligo(dT) primers contains
a random sequence or Unique
Molecular Identifier (UMI) as
such the corresponding
cDNA product is labelled
with a unique UMI
the gene detected in
the well, and the
expression level of this
gene (number of
mRNA molecules)
are reported
17
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evotec_Nov23_PanOmicsDriven

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