OVERCOMING mRNA PRODUCTION SCALE-UP CHALLENGES mood or reduce anxiety. In short, an mRNA vaccine can be used to express any protein and possibly treat almost any disease. GEN: What advice would you give to budding researchers interested in studying and working on mRNA vaccines? Langer: I think it's important to realize that there are few limits. Whether it's mRNA vaccines or anything else, I always tell my students to dream big dreams, dreams that can change the world. But if you do What Comes After the Success of SARS-CoV-2 mRNA Vaccines? Two field applications scientists at Thermo Fisher Scientific provides their perspectives on the potential of self-amplifying RNA and circular RNA in the future of drug development. Read the Article that you may run into obstacles. When I first discovered a way to deliver macromolecules including nucleic acids from small particles, I was ridiculed by the scientific community. My first nine research grants were rejected and no engineering department in the world would hire me for a faculty position. But I didn't give up and I always tell my students to never give up either. GEN wishes to thank David Olajide, consultant at CURZONPR in London, for providing the raw material for this article. GENengnews.com | 13https://www.thermofisher.com/us/en/home.html https://assets.thermofisher.com/TFS-Assets/BID/Reference-Materials/next-wave-rna-therapeutics-article.pdf?cid=bid_nat_mrw_r01_co_cp1531_pjt9473_ext3856_0db_gbn_eb_tls_an_s00_ https://www.genengnews.com