Scaling Up IVT for mRNA Production mization is needed for every mRNA construct, and remember that the process scale-up requirements can change based on size and sequence. Plan ahead-there may be a situaSummary The main challenge for efficient and effective mRNA process development is a lack of standard methodologies and practices. Thermo Fisher Scientific is committed to making standard products to help ensure consistent, robust, and reproducible workflows for IVT production. This means you can scale TheraPure GMP products are used in mRNA production on a global scale for vaccine and therapeutic development. The process includes DNA linearization, in vitro transcription, mRNA capping and tailing, purification, and analysis. mRNA production as required while maintaining consistent product quality, and reap rewards with rapid acceleration in the development of future mRNA therapeutics. © 2022 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified. EXT3854 1022 tion when your product needs to be held while equipment or reagents are prepared for the next stage. Check how holding your product at room temperature or 2-8°C affects quality. " -Sirat Watch the Video 22 | GENengnews.comhttps://www.genengnews.com https://players.brightcove.net/3663210762001/XCI1AMd08_default/index.html?videoId=6310349184112&cid=bid_nat_mrw_r01_co_cp1531_pjt9473_ext3856_0db_gbn_eb_tls_an_s00_ https://www.genengnews.com