Analytical Solutions for mRNA Vaccines and Therapeutics Featured Products Product name Orbitrap Exploris 240 Mass Spectrometer Orbitrap Exploris 120 Mass Spectrometer Vanquish Horizon UHPLC System Vanquish Flex UHPLC System Vanquish Duo UHPLC System Vanquish Charged Aerosol Detector H Extension Kit for Automated Method Scouting, Vanquish LC Systems DNAPac RP HPLC Columns DNAPac PA200 Oligonucleotide HPLC Columns Accucore C30 HPLC Columns BioPharma Finder Software SMART Digest Bulk Magnetic RNase T1 Kit KingFisher Duo Prime Purification System Dynabeads™ Oligo(dT)25 Resources Application notes Characterization of mRNA 5' capping products using an LC-HRAM-MS/MS analytical platform and Thermo Scientific BioPharma Finder software solution Characterization of in vitro-transcribed (IVT) mRNA poly(A) tail by LC-HRAM-MS and BioPharma Finder 5.0 software Characterization of lipid nanoparticle (LNP) composition using UHPLC-CAD Characterization and quantification of lipid nanoparticle components and their impurities/degradants using LC-HRAM MS platform Simultaneous reversed-phase and anion-exchange method scouting with a dual system for mRNA impurity determination Publications Characterization and sequence mapping of large RNA and mRNA therapeutics using mass spectrometry Webinars On-demand: automated workflow for mRNA sequencing by high resolution LC-MS Learn more at thermofisher.com/vaccineanalysis For Research Use Only. Not for use in diagnostic procedures. © 2022 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified. XX000790-EN 0822M 38 | GENengnews.com Catalog number BRE725535 BRE725531 IQLAAAGABHFAPUMZZZ IQLAAAGABHFAPUMBJC VQDUO-DUALLC VH-D20-A 6036.0100 088919 082509 mRNA isolation beads 27826-252130 OPTON-30986 60120-101 5400110 61002https://www.genengnews.com https://www.thermofisher.com/order/catalog/product/BRE725535?SID=srch-srp-BRE725535 https://www.thermofisher.com/order/catalog/product/BRE725531?SID=srch-srp-BRE725531 https://www.thermofisher.com/order/catalog/product/IQLAAAGABHFAPUMZZZ?SID=srch-srp-IQLAAAGABHFAPUMZZZ https://www.thermofisher.com/order/catalog/product/IQLAAAGABHFAPUMBJC?SID=srch-srp-IQLAAAGABHFAPUMBJC https://www.thermofisher.com/order/catalog/product/VQDUO-INVERSE https://www.thermofisher.com/order/catalog/product/VF-D20-A?SID=srch-hj-VF-D20-A https://www.thermofisher.com/order/catalog/product/6036.0100?SID=srch-hj-6036.0100 https://www.thermofisher.com/order/catalog/product/088923 https://www.thermofisher.com/order/catalog/product/082509 https://www.thermofisher.com/order/catalog/product/27826-152130?SID=srch-hj-27826-152130 https://www.thermofisher.com/order/catalog/product/OPTON-30986?SID=srch-srp-OPTON-30986 https://www.thermofisher.com/order/catalog/product/60120-101 https://www.thermofisher.com/order/catalog/product/5400110?SID=srch-srp-5400110 https://www.thermofisher.com/order/catalog/product/61002?SID=srch-srp-61002 https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-001108-pb-lc-hram-ms-mrna-quantification-an001108-na-en.pdf https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-001183-bt-orbitrap-exploris-240-ms-mrna-hram-lc-ms-an001183-na-en.pdf https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-000465-uhplc-cad-lipid-nanoparticle-composition-an000465-na-en.pdf https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-000464-lc-hram-ms-lipid-nanoparticle-impurities-degradants-an000464-na-en.pdf https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-000471-hplc-vanquish-duo-mRNA-method-development-an000471-na-en.pdf https://pubs.acs.org/doi/10.1021/acs.analchem.2c00765 https://event.on24.com/wcc/r/3135808/3108C3071E17027AB62C6E9A68FB5B40 http://thermofisher.com/vaccineanalysis?cid=E.22CMD.PB102.03854.01 https://www.thermofisher.com/us/en/home.html https://www.genengnews.com