Horizon eBook - 16

Innovations in Cell-Based Screening * More Predictive Cell-Based Assays

VeraVec EC/SC co-culture successfully recreates the SC niche in vitro.
We take various SC populations, including [those of] hematopoietic,
hepatic, neural, and cartilaginous [origin], and put them on the
VeraVec ECs where SCs expand at a phenomenal pace.
"The beauty of this platform is that it works all the way from basic
research through therapy. For example, we are building toward clinical
applications and show that when expanded co-cultures are transplanted
into animals, VeraVec ECs secrete growth factors and aid in SC-facilitated
tissue regeneration."
Moreover, the fidelity of SC-like phenotypes or signatures
characteristic of heterogeneous primary cancer cell cultures can be
maintained with VeraVec ECs. In contrast, cancerous cells change
their phenotype rapidly in traditional culture. n

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Horizon eBook

Table of Contents for the Digital Edition of Horizon eBook

Contents
Horizon eBook - 1
Horizon eBook - 2
Horizon eBook - 3
Horizon eBook - Contents
Horizon eBook - 5
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Horizon eBook - 24
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