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Innovations in Cell-Based Screening * CRISPR-Cas9 Knockout Screening

References
1. Wang T, Wei JJ, Sabatini DM, Lander ES. Genetic screens in human cells using
the CRISPR-Cas9 system. Science, 343: 80-84 (2014).
2. Shalem O, Sanjana NE, Hartenian E, Shi X, Scott DA, Mikkelsen TS, Heckl D,
Ebert BL, Root DE, Doench JG, Zhang F. Genome-scale CRISPR-Cas9 knockout
screening in human cells. Science, 343: 84-87 (2014).
3. Koike-Yusa H, Li Y, Tan EP, Velasco-Herrera Mdel C, Yusa K. Genome-wide recessive
genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library.
Nat Biotechnol. 32: 267-273 (2014).
4. Zhou Y, Zhu S, Cai C, Yuan P, Li C, Huang Y, Wei W. High-throughput screening
of a CRISPR/Cas9 library for functional genomics in human cells. Nature,
509: 487-491 (2014).

Eric Rhodes (e.rhodes@horizondiscovery.com)
is SVP, R&D and CTO of Horizon Discovery.

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Horizon eBook

Table of Contents for the Digital Edition of Horizon eBook

Contents
Horizon eBook - 1
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Horizon eBook - Contents
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