PerkinElmer eBook - Next-Gen Sequencing - 5

The Next

Next Thing in Sequencing
Next-Gen Sequencing Is Preparing
To Navigate New Molecular Codescapes
Kathy Liszewski

T

hough it may seem to be navigating by
perceptibly unfixed stars, next-generation
sequencing (NGS) is journeying ever more
adventurously into the obscure, the rare, and
the confoundingly heterogeneous domains
within life's molecular codescapes.
NGS is already capable of producing billions
of short reads, and it can do so quickly and
economically. And NGS is reaching well beyond
genomics. For example, it is revolutionizing
transcriptomics through advances in RNA
sequencing (RNA-Seq). Yet, despite this
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dazzling progress, a number of significant
challenges remain.
These challenges were discussed at a recent
Oxford Global event, the "Seventh Annual Next
Generation Sequencing Congress." The event
provided a window through which attendees
could browse the NGS field's most daunting
obstacles. It also displayed technologies that
could allow these obstacles to be circumvented.
New capabilities and applications include the
removal of toxic, unwanted transcripts from

ADDITIONAL CONTENT
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PerkinElmer eBook - Next-Gen Sequencing

Table of Contents for the Digital Edition of PerkinElmer eBook - Next-Gen Sequencing