PHCbi-Panasonic eBook - 19

A P P L I C AT I O N N O T E

The Cleanroom Alternative
to CAR T-Cell Therapy and
Regenerative Medicine
Facilities
Steven Lynum
President, PHC Corporation of North America

Introduction

T

he evolution of regenerative medicine has
sharpened the focus on a chronic need for
reproducibility, reliability, and contaminationfree performance of basic laboratory equipment
essential to the process. Whether for research
or clinical applications, the need to tailor a suite
of laboratory equipment and instrumentation
required for regenerative medicine and CAR
T-cell therapy involves an examination of exist-

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ing facility capabilities, funding sources, oversight and compliance attributes, and throughput required for economic benefit.
Cell culture can be viewed from two positions:
transfusion cells such as T-cells, cord blood
and bone marrow, and culture cells such as
hybridomas and cancer cells. Application of cell
culture production typically includes rejuvenation and immune system steering, regeneration
and new tissue growth, and regeneration and
targeting for cellular therapy and drug delivery.
Most of these processes must be performed in

ADDITIONAL CONTENT

Cell Processing Work Stations
Scalable, cleanroom alternative that provides a
cost-efficient, aseptic environment in a compact
footprint.
Learn More

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PHCbi-Panasonic eBook

Table of Contents for the Digital Edition of PHCbi-Panasonic eBook