2021 BQ Journal Vol 42 - 21

CDC | NCIRD | Healthcare Workers and Employees: Learn About the New mRNA COVID-19 Vaccines
mRNA vaccines have been studied for influenza, Zika,
rabies, and cytomegalovirus (CMV). Recent technological
advancements in RNA biology and chemistry, as well as
delivery systems, have mitigated the challenges of these
vaccines and improved their stability and effectiveness.

Benefits of mRNA vaccines
mRNA vaccines have several benefits
compared to other types of vaccines,
including use of a non-infectious element,
shorter manufacturing times, and
potential for targeting multiple diseases.
mRNA vaccines can be developed in a laboratory using
readily available materials. This means the process can be
standardized and scaled up, making vaccine development
faster than traditional methods. In the future, mRNA vaccine
technology may allow for one vaccine to target multiple
diseases.

Beyond vaccines, numerous preclinical and clinical studies
have used mRNA to encode cancer antigens to stimulate
immune responses targeted at clearing or reducing
malignant tumors.

Related links
Talking to Patients about COVID-19 Vaccines
Patient Information: Understanding mRNA Vaccines
FDA's Vaccine Development 101
FDA's Emergency Use Authorization for Vaccines Explained
FDA Infographic: The Path for a COVID-19 Vaccine from Research to Emergency Use Authorization

Additional resources
Pardi N, Hogan MJ, Porter FW, Weissman D. mRNA Vaccines-a New Era in Vaccinology. Nature Reviews. Drug Discovery.

2018;17(4):261.

Maruggi G, Zhang C, Li J, Ulmer JB, Yu D. mRNA as a Transformative Technology for Vaccine Development to Control

Infectious Diseases. Molecular Therapy. 2019;27(4):757-72.

Jackson NAC, Kester KE, Casimiro D, Gurunathan S, DeRosa F. The Promise of mRNA Vaccines: A Biotech and Industrial

Perspective. Npj Vaccines. 2020;5(1):1-6.

Diagnostics I Pharmaceuticals I DxRx Solutions I Continuing Education I News
21

A Henry Schein Publication

2021 BQ Journal Vol 42

Table of Contents for the Digital Edition of 2021 BQ Journal Vol 42

Table of Contents
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