2021 BQ Journal Vol 42 - 8

The investigators note that ECMO improved survival because it allowed time for a full team-based program of
care to be implemented. The program included protocols for emergency medical services to identify patients
who might benefit most from it. It also involved rapid transport to a hospital, communication with an ECMO
center to mobilize experienced operators who do a high volume of ECMO procedures, and protocols for care
after the patient is resuscitated.
" The findings from the trial make an important statement that early implementation of ECMO is the enabling
and necessary condition that allows further advanced targeted therapies to be delivered in those critical
patients. In its absence, the life-saving treatment that follows is just not possible, " says Yannopoulos.
While the results of this small trial are very encouraging, the use of ECMO will need to be tested in a larger,
multicenter trial.
References: Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory
ventricular fibrillation (ARREST): a phase 2, single centre, open-label, randomised controlled trial.
Yannopoulos D, Bartos J, Raveendran G, Walser E, Connett J, Murray TA, Collins G, Zhang L, Kalra R,
Kosmopoulos M, John R, Shaffer A, Frascone RJ, Wesley K, Conterato M, Biros M, Tolar J, Aufderheide
TP. Lancet. 2020 Nov 12:S0140-6736(20)32338-2. doi: 10.1016/S0140-6736(20)32338-2. Online ahead of print.
PMID: 33197396.
Funding: NIH'S National Heart, Lung, and Blood Institute (NHLBI).
Source:
https://www.nih.gov/news-events/nih-research-matters/life-support-machine-helps-cardiac-arrest-patients-survive

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2021 BQ Journal Vol 42

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