Medical - Vaccine Guide 2022 - 15

Notes Recommended Child and Adolescent Immunization Schedule for ages 18 years or younger, United States, 2022
Hepatitis A vaccination
(minimum age: 12 months for routine vaccination)
Routine vaccination
y 2-dose series (minimum interval: 6 months) at age 12-23 months
Catch-up vaccination
y Unvaccinated persons through age 18 years should complete a
2-dose series (minimum interval: 6 months).
y Persons who previously received 1 dose at age 12 months or older
should receive dose 2 at least 6 months after dose 1.
y Adolescents age 18 years or older may receive the combined HepA
and HepB vaccine, Twinrix®, as a 3-dose series (0, 1, and 6 months) or
4-dose series (3 doses at 0, 7, and 21-30 days, followed by a booster
dose at 12 months).
International travel
y Persons traveling to or working in countries with high or intermediate
endemic hepatitis A (www.cdc.gov/travel/):
- Infants age 6-11 months: 1 dose before departure; revaccinate
with 2 doses, separated by at least 6 months, between age 12-23
months.
- Unvaccinated age 12 months or older: Administer dose 1 as soon
as travel is considered.
Hepatitis B vaccination
(minimum age: birth)
Birth dose (monovalent HepB vaccine only)
y Mother is HBsAg-negative:
- All medically stable infants ≥2,000 grams: 1 dose within 24 hours of
birth
- Infants <2,000 grams: Administer 1 dose at chronological age
1 month or hospital discharge (whichever is earlier and even if
weight is still <2,000 grams).
y Mother is HBsAg-positive:
- Administer HepB vaccine and hepatitis B immune globulin (HBIG)
(in separate limbs) within 12 hours of birth, regardless of birth
weight. For infants <2,000 grams, administer 3 additional doses of
vaccine (total of 4 doses) beginning at age 1 month.
- Test for HBsAg and anti-HBs at age 9-12 months. If HepB series is
delayed, test 1-2 months after final dose.
y Mother's HBsAg status is unknown:
- Administer HepB vaccine within 12 hours of birth, regardless of
birth weight.
- For infants <2,000 grams, administer HBIG in addition to HepB
vaccine (in separate limbs) within 12 hours of birth. Administer 3
additional doses of vaccine (total of 4 doses) beginning at age 1
month.
- Determine mother's HBsAg status as soon as possible. If mother is
HBsAg-positive, administer HBIG to infants ≥2,000 grams as soon as
possible, but no later than 7 days of age.
Routine series
y 3-dose series at age 0, 1-2, 6-18 months (use monovalent HepB
vaccine for doses administered before age 6 weeks)
y Infants who did not receive a birth dose should begin the series as
soon as feasible (see Table 2).
22MS6015
y Administration of 4 doses is permitted when a combination vaccine
containing HepB is used after the birth dose.
or 4th
yMinimum age for the final (3rd
) dose: 24 weeks
yMinimum intervals: dose 1 to dose 2: 4 weeks / dose 2 to dose 3:
8 weeks / dose 1 to dose 3: 16 weeks (when 4 doses are administered,
substitute " dose 4 " for " dose 3 " in these calculations)
Catch-up vaccination
y Unvaccinated persons should complete a 3-dose series at 0, 1-2, 6
months.
y Adolescents age 11-15 years may use an alternative 2-dose
schedule with at least 4 months between doses (adult formulation
Recombivax HB® only).
y Adolescents age 18 years or older may receive a 2-dose series of HepB
(Heplisav-B®) at least 4 weeks apart.
y Adolescents age 18 years or older may receive the combined HepA
and HepB vaccine, Twinrix®, as a 3-dose series (0, 1, and 6 months) or
4-dose series (3 doses at 0, 7, and 21-30 days, followed by a booster
dose at 12 months).
y For other catch-up guidance, see Table 2.
Special situations
y Revaccination is not generally recommended for persons with a
normal immune status who were vaccinated as infants, children,
adolescents, or adults.
y Post-vaccination serology testing and revaccination (if anti-HBs <
10mlU/mL) is recommended for certain populations, including:
- Infants born to HBsAg-positive mothers
- Hemodialysis patients
- Other immunocompromised persons
For detailed revaccination recommendations, see www.cdc.gov/
vaccines/hcp/acip-recs/vacc-specific/hepb.html.
Human papillomavirus vaccination
(minimum age: 9 years)
Routine and catch-up vaccination
y HPV vaccination routinely recommended at age 11-12 years (can
start at age 9 years) and catch-up HPV vaccination recommended for
all persons through age 18 years if not adequately vaccinated
y 2- or 3-dose series depending on age at initial vaccination:
- Age 9-14 years at initial vaccination: 2-dose series at 0, 6-12
months (minimum interval: 5 months; repeat dose if administered
too soon)
- Age 15 years or older at initial vaccination: 3-dose series at 0, 1-2
months, 6 months (minimum intervals: dose 1 to dose 2: 4 weeks /
dose 2 to dose 3: 12 weeks / dose 1 to dose 3: 5 months; repeat dose
if administered too soon)
y Interrupted schedules: If vaccination schedule is interrupted, the
series does not need to be restarted.
y No additional dose recommended when any HPV vaccine series has
been completed using the recommended dosing intervals.
Special situations
y Immunocompromising conditions, including HIV infection:
3-dose series, even for those who initiate vaccination at age 9 through
14 years.
y History of sexual abuse or assault: Start at age 9 years.
15
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y Pregnancy: Pregnancy testing not needed before vaccination; HPV
vaccination not recommended until after pregnancy; no intervention
needed if vaccinated while pregnant
Influenza vaccination
(minimum age: 6 months [IIV], 2 years [LAIV4],
18 years [recombinant influenza vaccine, RIV4])
Routine vaccination
y Use any influenza vaccine appropriate for age and health status
annually:
- 2 doses, separated by at least 4 weeks, for children age 6 months-8
years who have received fewer than 2 influenza vaccine doses
before July 1, 2021, or whose influenza vaccination history is
unknown (administer dose 2 even if the child turns 9 between
receipt of dose 1 and dose 2)
- 1 dose for children age 6 months-8 years who have received at
least 2 influenza vaccine doses before July 1, 2021
- 1 dose for all persons age 9 years or older
y For the 2021-2022 season, see www.cdc.gov/mmwr/volumes/70/rr/
rr7005a1.htm.
y For the 2022-23 season, see the 2022-23 ACIP influenza vaccine
recommendations.
Special situations
y Egg allergy, hives only: Any influenza vaccine appropriate for age
and health status annually
y Egg allergy with symptoms other than hives (e.g., angioedema,
respiratory distress) or required epinephrine or another emergency
medical intervention: see Appendix listing contraindications and
precautions
y Severe allergic reaction (e.g., anaphylaxis) to a vaccine
component or a previous dose of any influenza vaccine: see
Appendix listing contraindications and precautions
Measles, mumps, and rubella vaccination
(minimum age: 12 months for routine vaccination)
Routine vaccination
y 2-dose series at age 12-15 months, age 4-6 years
y MMR or MMRV may be administered
Note: For dose 1 in children age 12-47 months, it is recommended to
administer MMR and varicella vaccines separately. MMRV may be used if
parents or caregivers express a preference.
Catch-up vaccination
y Unvaccinated children and adolescents: 2-dose series at least 4 weeks
apart
y The maximum age for use of MMRV is 12 years.
y Minimum interval between MMRV doses: 3 months
Special situations
International travel
y Infants age 6-11 months: 1 dose before departure; revaccinate with
2-dose series at age 12-15 months (12 months for children in high-risk
areas) and dose 2 as early as 4 weeks later.
y Unvaccinated children age 12 months or older: 2-dose series at least
4 weeks apart before departure
http://www.cdc.gov/travel/ http://www.cdc.gov/mmwr/volumes/70/rr/rr7005a1.htm http://www.cdc.gov/mmwr/volumes/70/rr/rr7005a1.htm http://www.cdc.gov/vaccines/hcp/acip-recs/vacc-specific/hepb.html http://www.cdc.gov/vaccines/hcp/acip-recs/vacc-specific/hepb.html http://www.henryschein.com/medical

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