IEEE Solid-States Circuits Magazine - Winter 2022 - 80
All Circuits in Hermetic Housing
Scalable: Only
Two Wires
Required
pixels are based on silicon nanowire
microphotodiodes for higher photoresponsivity.
The system employs
only a two-wire transocular connector
and does not require video data
transmission, as the incident light
on the retina modulates the magnitude
of the stimulation pulses. Additional
system-level innovations
provide further power savings and
control charge balancing.
Wireless stimulator systems presOptically
Addressed
Nanowire Array: Proven
Long-Term Biocompatibility
(a)
Efficient Off-Implant Regulation and Charge Balancing:
Reduced Thermal Concerns
Amplitude and Phase Control
Tx
Hermetic
Housing
Charge Metering Feedback
(b)
ηrect × ηchop ≈ 80%
Nanowire MEA:
1,512 Electrodes
ent cascaded power losses due to
voltage regulation, dc-dc conversion,
and driving DACs. To reduce
power dissipation near sensitive
tissues, the design pushes voltage
regulation and charge-balanced
stimulation control off the implant
to an external wearable system. This
external power transmitter system
controls the global stimulation pulse
shape through the amplitude modulation
of a 13.56-MHz power carrier
wave that is rectified by the implant
and directly applied to the nanowire
MEA, achieving 73% RF-to-stimulation
power efficiency. Simultaneously,
the implantable SoC reports the
metered global charge output
through load shift keying on the
same single inductive link. Finally, a
calibration technique to compensate
for power fluctuations caused by eye
movements is presented. The biocompatible
packaging of the system
features a 1,512-channel MEA, and
the design principles are scalable
to a larger number of stimulation
sites, without additional headroom
power and interconnect difficulties
(see Figure 3). This project was a
collaboration between the University
of California, San Diego and Nanovision
Biosciences.
1 mm
(c)
FIGURE 3: (a) An overview of the innovations in the proposed optically addressed nanowire
MEA with charge-metered, off-implant regulation [4]. (b) The retinal prosthesis system with
hermetic packaging. (c) A detail of the subretinal nanowire MEA [8].
80 WINTER 2022
IEEE SOLID-STATE CIRCUITS MAGAZINE
2021 SSCS-Brain Best Paper
Award Honorable Mention
" A MEMS-Based Dynamic Light Focusing
System for Single-Cell Precision
in Optogenetics, " by Cem
Yalcin, Nathan T. Ersaro, George Bocchetti,
M. Meraj Ghanbari, Nick Antipa,
Sina F. Alamouti, Laura Waller,
Daniel Lopez, and Rikky Muller,
earned the second honorable mention.
The awardees proposed a
IEEE Solid-States Circuits Magazine - Winter 2022
Table of Contents for the Digital Edition of IEEE Solid-States Circuits Magazine - Winter 2022
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IEEE Solid-States Circuits Magazine - Winter 2022 - Cover1
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