METHODS Application of Size Exclusion Chromatography with Multiangle Light Scattering in the Analytical Development of a Preclinical Stage Gene Therapy Program B. Troxell, I-W. Tsai, K. Shah, C.I. Knuckles, S. Shelton, K. Lindsey, S.M.B. Cardenas, and T. Roberts Letter to the Editor: A Favorable Benefit-Risk Balance Maybe Expected with Replication-Defective Adenovirus-Mediated Interferon Gene Therapy for Cancer Treatment A. Qin Instructions for Authors can be found on our website at www.liebertpub.com/hum Cover Image: Nicholas Muzyczka, PhD (1947-2023) was one of the earliest scientists working in Adeno-Associated Virus gene therapy. His work helped to establish the foundation of our field and he was a mentor to numerous scientsts who went on to become prominent gene therapy researchers. This issue is dedicated to him and his career. Thank you, Nick. 339 325 www.liebertpub.com/humhttp://www.liebertpub.com/hum http://www.liebertpub.com/hum