MD Conference Express - ESC 2014 Congress in Review - US Version - (Page 8)

LEAD ADVISORS Robert P. Giugliano, MD, SM Brigham and Women's Hospital, USA Keith A.A. Fox, MBChB, FRCP, FESC ESC CPC Chair Marc P. Bonaca, MD, MPH Brigham and Women's Hospital, USA Jacob A. Udell, MD, MPH Toronto General Hospital, Canada Nihar R. Desai, MD, MPH Yale University, USA Matthew Cavender, MD, MPH Brigham and Women's Hospital, USA Dylan L. Steen, MD Brigham and Women's Hospital, USA Erin A. Bohula, MD, DPhil Brigham and Women's Hospital GLOBAL ADVISORY BOARD Ashraf Abdelkafy, MD Suez Canal University, Egypt John Anderson, MD ADA President, Medicine & Science Philip E. Aylward, BM BCh, PhD Flinders Medical Centre, Australia David A. Barbie, MD Dana-Farber Cancer Institute, USA Jeroen J. Bax, MD, PhD Leiden University, The Netherlands Alfred Bove, MD, PhD Temple University, USA David A. Braunreiter, MD Weill Cornell Medical College, USA Ramon Corbalán, MD Pontificia Universidad Católica, Chile Anthony J. Dalby, MB, ChB, FCP Milpark Hospital, South Africa Gaetano M. De Ferrari, MD University of Pavia, Italy Vrunda Bhavsar Desai, MD, FACOG Yale-New Haven Hospital, USA Jean-Pierre Després, PhD Université Laval, Canada Michael Farkouh, MD, MSc Peter Munk Cardiac Centre, University Health Network, Canada Vivian A. Fonseca, MD, FRCP Tulane University, USA Timothy J. Gardner, MD Christiana Care Center for Heart & Vascular Health, USA Leena Gandhi, MD, PhD Dana-Farber Cancer Institute, USA Gregory R. Giugliano, MD, SM Baystate Medical Center, USA Shom Goel, MD Dana-Farber Cancer Institute, USA Wolfram Goessling, MD, PhD Dana-Farber Cancer Institute, USA Andreas Goette, MD EHRA Scientific Programme Committee Chair, 2013 Eva Gonçalvesova, MD, PhD Past-President, Slovak Society of Cardiology Steven Mark Greenberg, MD, PhD Chair, International Stroke Conference David M. Jackman, MD Dana-Farber Cancer Institute, USA Nigel Key, MD University of North Carolina, USA Bindee Kuriya, MD, FRCPC, MS University of Toronto, Canada Matthew Latham Macer, MD Yale-New Haven Hospital, USA Megan C. Leary, MD Harvard Clinical Research Institute, USA Milan Luknar, MD National Institute of Cardiovascular Disease, Slovak Republic Elena M. Massarotti, MD Brigham and Women's Hospital, USA Raymond Massay, MD Past-President, Caribbean Cardiac Society Otto Metzger, MD Dana-Farber Cancer Institute, USA Michael Micksche, MD University of Vienna, Austria Kimmie Ng, MD, MPH Dana-Farber Cancer Institute, USA Fausto Pinto, MD University of Lisbon, Portugal Elizabeth Seaquist, MD ADA President-Elect, Medicine & Science Sara Tolaney, MD, MPH Dana-Farber Cancer Institute, USA Andrew Wagner, MD, PhD Dana-Farber Cancer Institute, USA Daryle Wayne, PhD, ARNP, FPB-BC Pasco-Hernando State College, USA Jeffrey Weitz, MD McMaster University, Canada Patrick Ying, MD NYU Langone Medical Center, USA Uwe Zeymer, MD Klinikum Ludwigshafen and Institut für Herzinfarktforschung Ludwigshafen, Germany PUBLISHER President Jennifer Goodwin Schünemann Vice President, Publishing Beth Johnson Editorial Project Director Claire Stanton Project Managers Audrey Birkett Cindy Borch Developmental Editors Jennifer Bray Caroline Reich Umair Shafique, MSc Laura Ware Your FREE access to ESC Congress content all year long www.escardio.org/365 Medical Writers Emma Hitt Nichols, PhD Brian Hoyle Mary Mosley Nicola Parry Society Relationship Manager Elizabeth Donohue Cover Designer Leonardo March Production Editor Stephanie Palermini Tel.: +1-617-370-8088 reports@goodwingroupintl.com www.mdconferencexpress.com 400 West Cummings Park Suite 4000 Woburn, MA 01801 USA The Publisher does not assume any legal liability or responsibility for the accuracy, completeness, or usefulness of the information supplied herein, nor for any opinion expressed. The Publisher, its agents, and employees will not be liable for any loss or damage arising directly or indirectly from the possession, publication, use of, or reliance on information obtained from this report. It is provided in good faith without express or implied warranty. Reference to any specific commercial product or service does not imply endorsement or recommendation by the Publisher. All articles are peer-reviewed and protected from any commercial influence. a product of © MD Conference Express®. All rights reserved. Neither this publication nor any part of it may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of The Goodwin Group International, LLC. MD Conference Express is a registered trademark of The Goodwin Group International, LLC. ISSN 1559-8977 ISSN 2155-756X IN THIS ISSUE Strategies to Prevent Stroke in Patients With AF Atrial fibrillation (AF) is a worldwide public health problem, with a prevalence of 10% to 15% after 80 years of age. The morbidity and mortality in AF is high. With regard to the outcomes of stroke, the attributable risk of AF increases sharply from 1.5% to 23.5% for ages 50 to 59 years and 80 to 89 years, respectively. See page 11. ALSO Overview of 2014 ESC Guidelines Clinical Trial Highlights Update on Resistant Hypertension ESC CONGRESS IN REVIEW OFFICIAL PEER-REVIEWED HIGHLIGHTS FROM ESC CONGRESS IN REVIEW Official Peer-Reviewed Highlights From ESC Congress 2014 FEATURES 9 Innovations in ACS Treatment 11 Strategies to Prevent Stroke in Patients With AF CLINICAL TRIAL HIGHLIGHTS 14 ODYSSEY COMBO II: Alirocumab Significantly Improves Cholesterol Levels in Patients With High CV Risk 15 PARADIGM-HF: Novel Drug Reduced Outcomes, Improved Symptoms Better Than ACE Inhibition 16 NECTAR-HF: Cardiac Remodeling Not Reduced With VNS 17 SIGNIFY: Treatment With Ivabradine Does Not Improve Outcomes and May Increase Risk in Patients With Angina 18 CONFIRM-HF: Novel Approach Treating ID Improved Function, Symptoms, and QOL 19 POPE-2: No Benefit With Colchicine to Reduce Persistent Postoperative Pericardial Effusion 19 COPPS-2: Colchicine Reduced PPS in Cardiac Surgery Patients 21 Darapladib Ineffective at Reducing Major Coronary Events After ACS 21 Prehospital Ticagrelor Reduces Stent Thrombosis in STEMI 22 ODYSSEY FH I and FH II: Alirocumab Significantly Improves Cholesterol Levels in Patients With HeFH 23 IBIS-4: High-Dose Rosuvastatin Reduces Plaque Burden in Patients With STEMI 24 NO Fails to Reduce Myocardial IS: NOMI Results 24 TRO40303 Lacks Protective Effect in PCI: Results From MITOCARE 25 ENGAGE AF-TIMI 48: Tailoring Edoxaban Dose Preserves Drug Efficacy and Safety 27 X-VeRT Results: Rivaroxaban Is Safe and Effective for Cardioversion in AF 27 FAMOUS NSTEMI: FFR- Guided Management of NSTEMI Reduces PCI and CABG 28 STABILITY: Darapladib and Lp-PLA2 Levels in Treatment of Atherosclerosis 30 FAME 2: FFR-Guided PCI Reduces Urgent Revascularization SELECTED UPDATES 31 Overview of 2014 ESC Guidelines 35 Reducing CV Outcomes in Patients With AF 38 Update on Resistant Hypertension PEER-REVIEWED HIGHLIGHTS CARDIOLOGY http://www.escardio.org/365 http://www.escardio.org/365 http://www.mdconferencexpress.com

Table of Contents for the Digital Edition of MD Conference Express - ESC 2014 Congress in Review - US Version

Contents

MD Conference Express - ESC 2014 Congress in Review - US Version

https://www.nxtbook.com/nxtbooks/md_conference_express/esc2014_congressinreview_us
https://www.nxtbookmedia.com