Hospital Pharmacy - December 2020 - Cover2
TOP THE
BLEEDING
Product Costs for Factor Concentrates
in von Willebrand Disease (VWD) Are Substantial
Converting to a von Willebrand factor/factor VIII concentrate (VWF/FVIII) that requires a
lower dose may reduce total product costs
Not all VWF/FVIII concentrates are the same.
There are distinct differences between some
widely-used VWF/FVIII concentrates-specifically,
the recommended dose and total product usage
needed to prevent and control bleeding.1-3
Product Cost for On-demand Treatment and
Perioperative Management of Bleeding1,8‡§
Product Cost per Bleeding Event
$9,981
59%
Cost Avoidance
Based on the reported dosing from selected pivotal
studies with wilate® and Humate-P®:1,4-7*
$4,051
n
In the on-demand setting, the median dose of
wilate was more than 112% lower than Humate-P
(26 vs 55 IU/kg)1†
n
In the surgical setting, the median loading dose
per infusion with wilate was almost 58% lower
than Humate-P (52 vs 82 IU/kg) and the median
maintenance dose per infusion was 82% lower
(29 vs 53 IU/kg)1†
Differences in product usage can have health
economics consequences. Based on the above data
and published ASP, total product costs for wilate would
be 59% lower vs Humate-P for on-demand treatment and
42% lower for perioperative management of bleeding.1,8‡§
Humate-P
wilate
Product Cost per Surgical Procedure
42%
Cost Avoidance
$31,112
$18,009
Humate-P
wilate
MAYBE IT'S TIME TO SWITCH YOUR VWF/FVIII PRODUCT
Indications and Usage
wilate® is indicated in children and adults with von Willebrand disease (VWD) for on-demand treatment and
control of bleeding episodes; and for the perioperative management of bleeding. wilate is also indicated in
adolescents and adults with hemophilia A for routine prophylaxis to reduce the frequency of bleeding episodes,
and for on-demand treatment and control of bleeding episodes.
Please see accompanying Highlights of Prescribing Information for additional important information.
Hospital Pharmacy - December 2020
Table of Contents for the Digital Edition of Hospital Pharmacy - December 2020
Drug Review Updated List of Light-Sensitive Oral Medications Scott Perkins, Adam Evans, and Allison King
Original Articles Prophylactic Enoxaparin Dosing in Obese Orthopedic Patients: A Literature Search Van N. Tran, Ilya Varfolomeev, and Geoff Hill
Significant Published Articles for Pharmacy Nutrition Support Practice in 2019 Roland N. Dickerson, Angela L. Bingham, Todd W. Canada, Lingtak N. Chan, M. Petrea Cober, Sarah V. Cogle, Anne M. Tucker, and Vanessa J. Kumpf
Effect of Therapeutic Interchange on Medication Changes Between Admission and Discharge Ryan A. Popp, Kathleen A. Lusk, Shelley S. Glaess, Donna Burkett, and Rebecca L. Attridge
Evaluating Six Commercially Available Closed-System Drug-Transfer Devices Against NIOSH’s 2015 Draft Vapor Protocol Shiraz Halloush, Ivan A. Reveles, and Jim Koeller
Adjusted vs Total Body Weight–Based Dosing of Sedation and Analgesia Used in the Intensive Care Unit Julianne Yeary, Alexandra Greco, Richard McKnight, Karen Petros, Gregory Schaefer, and Jeffrey Garavaglia
Medication Safety at Home: A Qualitative Study on Caregivers of Chronically Ill Children in Malaysia Chii-Chii Chew, Amar-Singh HSS, Huan-Keat Chan, and Mohamed Azmi Hassali
Hospital Pharmacy - December 2020 - Cover1
Hospital Pharmacy - December 2020 - Cover2
Hospital Pharmacy - December 2020 - 345
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Hospital Pharmacy - December 2020 - Drug Review Updated List of Light-Sensitive Oral Medications Scott Perkins, Adam Evans, and Allison King
Hospital Pharmacy - December 2020 - 350
Hospital Pharmacy - December 2020 - 351
Hospital Pharmacy - December 2020 - 352
Hospital Pharmacy - December 2020 - 353
Hospital Pharmacy - December 2020 - 354
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Hospital Pharmacy - December 2020 - 364
Hospital Pharmacy - December 2020 - 365
Hospital Pharmacy - December 2020 - Original Articles Prophylactic Enoxaparin Dosing in Obese Orthopedic Patients: A Literature Search Van N. Tran, Ilya Varfolomeev, and Geoff Hill
Hospital Pharmacy - December 2020 - 367
Hospital Pharmacy - December 2020 - 368
Hospital Pharmacy - December 2020 - 369
Hospital Pharmacy - December 2020 - 370
Hospital Pharmacy - December 2020 - 371
Hospital Pharmacy - December 2020 - 372
Hospital Pharmacy - December 2020 - Significant Published Articles for Pharmacy Nutrition Support Practice in 2019 Roland N. Dickerson, Angela L. Bingham, Todd W. Canada, Lingtak N. Chan, M. Petrea Cober, Sarah V. Cogle, Anne M. Tucker, and Vanessa J. Kumpf
Hospital Pharmacy - December 2020 - 374
Hospital Pharmacy - December 2020 - 375
Hospital Pharmacy - December 2020 - 376
Hospital Pharmacy - December 2020 - 377
Hospital Pharmacy - December 2020 - 378
Hospital Pharmacy - December 2020 - 379
Hospital Pharmacy - December 2020 - 380
Hospital Pharmacy - December 2020 - 381
Hospital Pharmacy - December 2020 - Effect of Therapeutic Interchange on Medication Changes Between Admission and Discharge Ryan A. Popp, Kathleen A. Lusk, Shelley S. Glaess, Donna Burkett, and Rebecca L. Attridge
Hospital Pharmacy - December 2020 - 383
Hospital Pharmacy - December 2020 - 384
Hospital Pharmacy - December 2020 - 385
Hospital Pharmacy - December 2020 - 386
Hospital Pharmacy - December 2020 - 387
Hospital Pharmacy - December 2020 - 388
Hospital Pharmacy - December 2020 - 389
Hospital Pharmacy - December 2020 - 390
Hospital Pharmacy - December 2020 - Evaluating Six Commercially Available Closed-System Drug-Transfer Devices Against NIOSH’s 2015 Draft Vapor Protocol Shiraz Halloush, Ivan A. Reveles, and Jim Koeller
Hospital Pharmacy - December 2020 - 392
Hospital Pharmacy - December 2020 - 393
Hospital Pharmacy - December 2020 - 394
Hospital Pharmacy - December 2020 - 395
Hospital Pharmacy - December 2020 - 396
Hospital Pharmacy - December 2020 - 397
Hospital Pharmacy - December 2020 - 398
Hospital Pharmacy - December 2020 - 399
Hospital Pharmacy - December 2020 - Adjusted vs Total Body Weight–Based Dosing of Sedation and Analgesia Used in the Intensive Care Unit Julianne Yeary, Alexandra Greco, Richard McKnight, Karen Petros, Gregory Schaefer, and Jeffrey Garavaglia
Hospital Pharmacy - December 2020 - 401
Hospital Pharmacy - December 2020 - 402
Hospital Pharmacy - December 2020 - 403
Hospital Pharmacy - December 2020 - 404
Hospital Pharmacy - December 2020 - Medication Safety at Home: A Qualitative Study on Caregivers of Chronically Ill Children in Malaysia Chii-Chii Chew, Amar-Singh HSS, Huan-Keat Chan, and Mohamed Azmi Hassali
Hospital Pharmacy - December 2020 - 406
Hospital Pharmacy - December 2020 - 407
Hospital Pharmacy - December 2020 - 408
Hospital Pharmacy - December 2020 - 409
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Hospital Pharmacy - December 2020 - Cover3
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