Hospital Pharmacy - February 2020 - 39
39
AbuAlsaud et al
Figure 1. Proportion of practitioners familiar with the definition of off-label prescribing.
Table 2. Off-label Prescribing by Practitioners: Experiences and Views Regarding Medicines for Children.
Items
Overall
General practitioner Pediatrician Specialist P valuea
First time heard about off-label prescribing during
Undergraduate studies
25 (16%)
17 (15%)
Post-graduate studies
40 (25%)
22 (19%)
Through my experience
36 (23%)
24 (21%)
Terminology was new to me
59 (37%)
51 (45%)
Frequency of off-label prescription to children during the previous year
≤10%
112 (70%)
80 (70%)
11%-25%
34 (21%)
27 (24%)
≥26%
14 (9%)
7 (6%)
Concerns about the efficacy of off-label prescribing to children
Yes, major concerns
57 (36%)
35 (31%)
Yes, minor concerns
76 (48%)
56 (49%)
No, no concerns at all
27 (17%)
23 (20%)
Concerns about the safety of off-label prescribing to children
Yes, major concerns
80 (50%)
50 (44%)
Yes, minor concerns
67 (42%)
51 (45%)
No, no concerns at all
13 (8%)
13 (11%)
Ever experienced an adverse drug reaction following off-label prescribing medicines to childrenb
Yes
23 (20%)
18 (22%)
No
94 (80%)
63 (78%)
Ever experienced treatment failure following off-label prescribing of medicines to childrenb
Yes
43 (37%)
28 (35%)
No
74 (63%)
53 (65%)
Most likely recipient of off-label prescriptions among children
Neonates, including preterm and term from birth to 28 days
15 (9%)
6 (5%)
Infants (1-23 months old)
41 (26%)
30 (26%)
Children 2-11 years old
68 (43%)
54 (47%)
Children 12-16 years old
36 (23%)
24 (21%)
a
Chi-square/Fishers exact test used.
Forty participants did not answer.
b
2 (8%)
12 (46%)
8 (31%)
4 (15%)
6 (30%)
6 (30%)
4 (20%)
4 (20%)
.006
14 (54%)
6 (23%)
6 (23%)
18 (90%)
1 (5%)
1 (5%)
.020
9 (35%)
13 (50%)
4 (15%)
13 (65%)
7 (35%)
0 (0%)
.030
15 (58%)
11 (42%)
0 (0%)
15 (75%)
5 (25%)
0 (0%)
.038
2 (10%)
18 (90%)
3 (19%)
13 (81%)
.549
8 (40%)
12 (60%)
7 (44%)
9 (56%)
.743
8 (31%)
6 (23%)
8 (31%)
4 (15%)
1 (5%)
5 (25%)
6 (30%)
8 (40%)
.009
Hospital Pharmacy - February 2020
Table of Contents for the Digital Edition of Hospital Pharmacy - February 2020
TOC/Verso
CBD: Considerations for Use Within the Health System
Early Acute Ischemic Stroke Management for Pharmacists
Impact of the Sequence of Norepinephrine and Vasopressin Discontinuation in Patients Recovering From Septic Shock
Evaluation of a Long-Acting Opioid Restriction Policy: Does Restriction Reduce the Need for Naloxone Reversal?
Off-label Medications Use in the Eastern Province of Saudi Arabia: The Views of General Practitioners, Pediatricians, and Other Specialists
Piperacillin-Tazobactam Versus Carbapenems for the Treatment of Nonbacteremic Urinary Tract Infections due to Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae
Factors Associated With Increased Hospital Length of Stay in Peritoneal Dialysis Patients With Peritonitis: A Need for Antimicrobial Stewardship?
The Clinical and Financial Impact of a Pharmacist-Driven Penicillin Skin Testing Program on Antimicrobial Stewardship Practices
Prolonged Versus Short Infusion Rates of IV Magnesium in Hospitalized General Medicine Patients with Hypomagnesemia
Ischemic Stroke Symptoms After Warfarin Reversal With 4-Factor Prothrombin Complex Concentrate Case Report
Hospital Pharmacy - February 2020 - TOC/Verso
Hospital Pharmacy - February 2020 - Cover2
Hospital Pharmacy - February 2020 - 1
Hospital Pharmacy - February 2020 - 2
Hospital Pharmacy - February 2020 - 3
Hospital Pharmacy - February 2020 - 4
Hospital Pharmacy - February 2020 - 5
Hospital Pharmacy - February 2020 - 6
Hospital Pharmacy - February 2020 - 7
Hospital Pharmacy - February 2020 - 8
Hospital Pharmacy - February 2020 - CBD: Considerations for Use Within the Health System
Hospital Pharmacy - February 2020 - 10
Hospital Pharmacy - February 2020 - 11
Hospital Pharmacy - February 2020 - Early Acute Ischemic Stroke Management for Pharmacists
Hospital Pharmacy - February 2020 - 13
Hospital Pharmacy - February 2020 - 14
Hospital Pharmacy - February 2020 - 15
Hospital Pharmacy - February 2020 - 16
Hospital Pharmacy - February 2020 - 17
Hospital Pharmacy - February 2020 - 18
Hospital Pharmacy - February 2020 - 19
Hospital Pharmacy - February 2020 - 20
Hospital Pharmacy - February 2020 - 21
Hospital Pharmacy - February 2020 - 22
Hospital Pharmacy - February 2020 - 23
Hospital Pharmacy - February 2020 - 24
Hospital Pharmacy - February 2020 - 25
Hospital Pharmacy - February 2020 - Impact of the Sequence of Norepinephrine and Vasopressin Discontinuation in Patients Recovering From Septic Shock
Hospital Pharmacy - February 2020 - 27
Hospital Pharmacy - February 2020 - 28
Hospital Pharmacy - February 2020 - 29
Hospital Pharmacy - February 2020 - 30
Hospital Pharmacy - February 2020 - 31
Hospital Pharmacy - February 2020 - Evaluation of a Long-Acting Opioid Restriction Policy: Does Restriction Reduce the Need for Naloxone Reversal?
Hospital Pharmacy - February 2020 - 33
Hospital Pharmacy - February 2020 - 34
Hospital Pharmacy - February 2020 - 35
Hospital Pharmacy - February 2020 - 36
Hospital Pharmacy - February 2020 - Off-label Medications Use in the Eastern Province of Saudi Arabia: The Views of General Practitioners, Pediatricians, and Other Specialists
Hospital Pharmacy - February 2020 - 38
Hospital Pharmacy - February 2020 - 39
Hospital Pharmacy - February 2020 - 40
Hospital Pharmacy - February 2020 - 41
Hospital Pharmacy - February 2020 - 42
Hospital Pharmacy - February 2020 - 43
Hospital Pharmacy - February 2020 - Piperacillin-Tazobactam Versus Carbapenems for the Treatment of Nonbacteremic Urinary Tract Infections due to Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae
Hospital Pharmacy - February 2020 - 45
Hospital Pharmacy - February 2020 - 46
Hospital Pharmacy - February 2020 - 47
Hospital Pharmacy - February 2020 - 48
Hospital Pharmacy - February 2020 - 49
Hospital Pharmacy - February 2020 - Factors Associated With Increased Hospital Length of Stay in Peritoneal Dialysis Patients With Peritonitis: A Need for Antimicrobial Stewardship?
Hospital Pharmacy - February 2020 - 51
Hospital Pharmacy - February 2020 - 52
Hospital Pharmacy - February 2020 - 53
Hospital Pharmacy - February 2020 - 54
Hospital Pharmacy - February 2020 - 55
Hospital Pharmacy - February 2020 - 56
Hospital Pharmacy - February 2020 - 57
Hospital Pharmacy - February 2020 - The Clinical and Financial Impact of a Pharmacist-Driven Penicillin Skin Testing Program on Antimicrobial Stewardship Practices
Hospital Pharmacy - February 2020 - 59
Hospital Pharmacy - February 2020 - 60
Hospital Pharmacy - February 2020 - 61
Hospital Pharmacy - February 2020 - 62
Hospital Pharmacy - February 2020 - 63
Hospital Pharmacy - February 2020 - Prolonged Versus Short Infusion Rates of IV Magnesium in Hospitalized General Medicine Patients with Hypomagnesemia
Hospital Pharmacy - February 2020 - 65
Hospital Pharmacy - February 2020 - 66
Hospital Pharmacy - February 2020 - 67
Hospital Pharmacy - February 2020 - 68
Hospital Pharmacy - February 2020 - Ischemic Stroke Symptoms After Warfarin Reversal With 4-Factor Prothrombin Complex Concentrate Case Report
Hospital Pharmacy - February 2020 - 70
Hospital Pharmacy - February 2020 - 71
Hospital Pharmacy - February 2020 - 72
Hospital Pharmacy - February 2020 - Cover3
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