Hospital Pharmacy - June 2018 - 183
183
Shanko and Abdela
Table 5. Practices of ADR Reporting Among Health Care Professionals at HFSUH, Harar, Eastern Ethiopia, From February to March
2015.
Professions
Variables
Nurses
230 (%)
Physicians
44 (%)
Pharmacists
21 (%)
Total
295 (%)
Pearson
chi-square
P value
Have you ever encountered patients with ADR in your clinical practice in the last 12 months?
Yes
102 (44.3)
32 (72.7)
11 (52.4)
145 (49.2)
11.816
No
127 (55.2)
12 (27.3)
10 (47.6)
149 (50.5)
How many patients with ADR did you see?
One
21 (9.13)
6
3
30 (10.17)
13.972
Two
30 (13.04)
6
5
41 (13.9)
Three
20 (8.7)
13 (29.55)
1
34 (11.53)
Four
14 (6.1)
6
-
20 (6.78)
Above four
18 (7.83)
1
2
21 (7.12)
Have you noted down the ADR you encountered on the patient clinical record?
Yes
75 (32.61)
28 (63.64)
7 (33.3%)
110 (37.3)
4.150
No
28 (12.17)
4
4
36 (12.2)
Have you ever reported the ADRs?
Yes
134 (58.26)
34 (77.27)
11 (52.4)
179 (60.68)
6.139
No
95 (41.3)
10 (22.73)
10 (47.6)
115 (38.98)
Where did you report that reaction?
Hospital
67 (29.13)
26 (59.1)
9 (42.86)
102 (34.58)
15.125
Pharmaceutical company
33 (14.35)
7
1
41 (13.9)
FMHACA
2 (0.87)
-
-
2
Doctor
37 (16.1)
1
1
39 (13.22)
How often do you give advice to your patients on possible adverse effects of drugs you prescribed, dispensed, or administered?
Usually
69 (30)
18 (40.91)
14 (66.67)
101 (34.24)
14.842
Sometimes
147 (63.91)
26 (59.1)
7 (33.33)
180 (61.02)
Never
12 (5.22)
-
-
12 (4.07)
.002
.083
.386
.046
.019
.022
Note. Association is done using Pearson chi-square test, P < .05 considered to be statistically significant. HFSUH = Hiwot Fana Specialized University
Hospital; ADR = adverse drug reaction; FMHACA = Food, Medicine and Health Care Administration and Control Authority.
increases with length of work experience20 as well as it is not
consistent with the study conducted in West Ethiopia.18
On the other hand, our study showed that about 70.5% of the
study participants had no information about pharmacovigilance.
This could be attributed to the absence of ADR-related education, in-service training, and encouraging and establishing ADR
reporting committee,21 and lack of motivation and feedback
from FMHACA has its own impact. These could lead to underreporting of ADR which leads to high risk of serious ADR
exposure among the individuals and negatively affect the quality of life of patients.22 Despite that, pharmacists were reported
to be more knowledgeable than the remaining health care professionals (P < .05) with regard to the pharmacovigilance system. In fact, this may demonstrate that pharmacists have more
access to information related to drugs and their negative consequence on the health of individuals compared with other health
care professionals. This finding is concordant with the results
reported from a study conducted at Nekemte Hospital, in which
pharmacists were better able to recognize the term pharmacovigilance.18 However, our results are not in agreement with the
study conducted in Jordan, in which Pharmacists had poor
knowledge about the pharmacovigilance system.23
Our study also indicated that 61.69% of the respondents
knew at least one of the means of ADR reporting, whereas
38.3% of the participants did not know any methods of ADR
reporting. Although more than half of the respondents knew
methods of ADR reporting, still knowledge gaps were observed
among health care professionals that could undermine proper
handling and reporting of ADR. In terms of professions,
81.82% of physicians and 85.71% of pharmacists were found
to be more knowledgeable than nurses on how to report ADR.
This might indicate poor team work and information sharing
among these health care professionals that could lead to
unequal distribution of knowledge on how to report ADR.
Concerning the knowledge on ADR documentation at the
time of marketing, 52.53% of respondents believed that ADR
is well documented at the time of marketing, whereas 48.47%
of the participants did not agree it. This could be resulted
from poor awareness about new ADRs likely to be associated
with the drugs after marketing due to exposure of a large
group of population with various characteristics and genetic
makeup that contribute to unusual reactions not ever reported.
Therefore, the presence of such perceptions among health
care professionals attributed to undermining early detection
Table of Contents for the Digital Edition of Hospital Pharmacy - June 2018
Ed Board
TOC
USP <800>
Oct-Dec 2017 Boxed Warning Highlights approved by the FDA
Zoster Vaccine Recombinant, Adjuvanted
Multifactorial Causes of Tacrolimus Errors: Confusion With Strength/Formulation, Look-Alike Names, Preparation Errors, and More
New Medications in the Treatment of Nonalcoholic Steatohepatitis
One Chance for Your Best First Impression: Tips for New Pharmacists
Implications of Statin Use on Vasopressor Therapy in the Setting of Septic Shock
Intravenous Push Administration of Antibiotics: Literature and Considerations
The Role of Computerized Clinical Decision Support in Reducing Inappropriate Medication Administration During Epidural Therapy
Health Care Professionals Toward Adverse Drug Reaction Reporting in Hiwot Fana Specialized University Hospital, Harar, Eastern Ethiopia: A Cross-sectional Study
Nonpharmacist Health Care Providers’ Knowledge of and Opinions Regarding Medication Costs in Critically Ill Patients
Detection of HBV, HCV, and Incidence of Febrile Neutropenia Associated With CHOP With or Without Rituximab in Diffuse Large B-Cell Lymphoma–Treated Patients
Hospital Pharmacy - June 2018 - Cover1
Hospital Pharmacy - June 2018 - Cover2
Hospital Pharmacy - June 2018 - Ed Board
Hospital Pharmacy - June 2018 - TOC
Hospital Pharmacy - June 2018 - 131
Hospital Pharmacy - June 2018 - USP <800>
Hospital Pharmacy - June 2018 - 133
Hospital Pharmacy - June 2018 - Oct-Dec 2017 Boxed Warning Highlights approved by the FDA
Hospital Pharmacy - June 2018 - 135
Hospital Pharmacy - June 2018 - Zoster Vaccine Recombinant, Adjuvanted
Hospital Pharmacy - June 2018 - 137
Hospital Pharmacy - June 2018 - 138
Hospital Pharmacy - June 2018 - 139
Hospital Pharmacy - June 2018 - 140
Hospital Pharmacy - June 2018 - 141
Hospital Pharmacy - June 2018 - Multifactorial Causes of Tacrolimus Errors: Confusion With Strength/Formulation, Look-Alike Names, Preparation Errors, and More
Hospital Pharmacy - June 2018 - 143
Hospital Pharmacy - June 2018 - 144
Hospital Pharmacy - June 2018 - 145
Hospital Pharmacy - June 2018 - New Medications in the Treatment of Nonalcoholic Steatohepatitis
Hospital Pharmacy - June 2018 - 147
Hospital Pharmacy - June 2018 - One Chance for Your Best First Impression: Tips for New Pharmacists
Hospital Pharmacy - June 2018 - 149
Hospital Pharmacy - June 2018 - 150
Hospital Pharmacy - June 2018 - 151
Hospital Pharmacy - June 2018 - Implications of Statin Use on Vasopressor Therapy in the Setting of Septic Shock
Hospital Pharmacy - June 2018 - 153
Hospital Pharmacy - June 2018 - 154
Hospital Pharmacy - June 2018 - 155
Hospital Pharmacy - June 2018 - 156
Hospital Pharmacy - June 2018 - Intravenous Push Administration of Antibiotics: Literature and Considerations
Hospital Pharmacy - June 2018 - 158
Hospital Pharmacy - June 2018 - 159
Hospital Pharmacy - June 2018 - 160
Hospital Pharmacy - June 2018 - 161
Hospital Pharmacy - June 2018 - 162
Hospital Pharmacy - June 2018 - 163
Hospital Pharmacy - June 2018 - 164
Hospital Pharmacy - June 2018 - 165
Hospital Pharmacy - June 2018 - 166
Hospital Pharmacy - June 2018 - 167
Hospital Pharmacy - June 2018 - 168
Hospital Pharmacy - June 2018 - 169
Hospital Pharmacy - June 2018 - The Role of Computerized Clinical Decision Support in Reducing Inappropriate Medication Administration During Epidural Therapy
Hospital Pharmacy - June 2018 - 171
Hospital Pharmacy - June 2018 - 172
Hospital Pharmacy - June 2018 - 173
Hospital Pharmacy - June 2018 - 174
Hospital Pharmacy - June 2018 - 175
Hospital Pharmacy - June 2018 - 176
Hospital Pharmacy - June 2018 - Health Care Professionals Toward Adverse Drug Reaction Reporting in Hiwot Fana Specialized University Hospital, Harar, Eastern Ethiopia: A Cross-sectional Study
Hospital Pharmacy - June 2018 - 178
Hospital Pharmacy - June 2018 - 179
Hospital Pharmacy - June 2018 - 180
Hospital Pharmacy - June 2018 - 181
Hospital Pharmacy - June 2018 - 182
Hospital Pharmacy - June 2018 - 183
Hospital Pharmacy - June 2018 - 184
Hospital Pharmacy - June 2018 - 185
Hospital Pharmacy - June 2018 - 186
Hospital Pharmacy - June 2018 - 187
Hospital Pharmacy - June 2018 - Nonpharmacist Health Care Providers’ Knowledge of and Opinions Regarding Medication Costs in Critically Ill Patients
Hospital Pharmacy - June 2018 - 189
Hospital Pharmacy - June 2018 - 190
Hospital Pharmacy - June 2018 - 191
Hospital Pharmacy - June 2018 - 192
Hospital Pharmacy - June 2018 - 193
Hospital Pharmacy - June 2018 - Detection of HBV, HCV, and Incidence of Febrile Neutropenia Associated With CHOP With or Without Rituximab in Diffuse Large B-Cell Lymphoma–Treated Patients
Hospital Pharmacy - June 2018 - 195
Hospital Pharmacy - June 2018 - 196
Hospital Pharmacy - June 2018 - 197
Hospital Pharmacy - June 2018 - 198
Hospital Pharmacy - June 2018 - 199
Hospital Pharmacy - June 2018 - 200
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