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antibiotic use or clinical pathway for every type of surgery,
including any complicated surgery and other infectious diseases. Antibiotics should be selected more precisely, dosage
and frequency are to be improved, and appropriate route of
administration needs to be enhanced. We recommend single
dose administration of single narrow spectrum antibiotic
within a period of no more than 24 hours for surgical prophylaxis to prevent microbial resistant incidence. Hence, the
results of our study are valuable for future policy making in
this field. Creating awareness among medical staff, adaptation of antibiotic use policy by the Indonesian government,
and continuous monitoring and adjustment to improve will
lead to an improved Indonesian health care system with
respect to rational prophylactic antibiotic use.
Acknowledgments
This study was conducted in the framework of a collaboration
agreement between the Faculty of Pharmacy University of
Surabaya, Indonesia, and the Groningen Research Institute of
Pharmacy, Faculty of Science and Engineering, University of
Groningen, the Netherlands. The authors would like to thank the
management of the two hospitals for allowing them to collect the
data from the patient files and to use them for the evaluation. They
also thank the staff for their cooperation, hospitality, and friendliness. They would like to thank to Erik Christopher, Klinik Bahasa,
Faculty Kedokteran, Universitas Gadjah Mada (Yogyakarta) for
helping to edit the manuscript.

Declaration of Conflicting Interests
The author(s) declared no potential conflicts of interest with respect
to the research, authorship, and/or publication of this article.

Funding
The author(s) received no financial support for the research, authorship, and/or publication of this article.

ORCID iD
Fauna Herawati

https://orcid.org/0000-0002-8355-955X

Supplemental Material
Supplemental material for this article is available online.

References
1. Owens RC, Donskey CJ, Gaynes RP, Loo VG, Muto CA.
Antimicrobial-associated risk factors for Clostridium difficile infection. Clin Infect Dis. 2008;46(suppl 1):S19-S31.
doi:10.1086/521859.
2. Enzler MJ, Berbari E, Osmon DR. Antimicrobial prophylaxis
in adults. Mayo Clin Proc. 2011;86(7):686-701. doi:10.4065/
mcp.2011.0012.
3. World Health Organization. Antimicrobial resistance: global
report on surveillance. Published 2014. http://www.who.int/
drugresistance/documents/surveillancereport/en.
Accessed
July 26, 2018.

4. Lee CF, Cowling BJ, Feng S, et al. Impact of antibiotic stewardship programmes in Asia: a systematic review and meta-analysis. J Antimicrob Chemother. 2018;73(4):844-851. doi:10.1093/
jac/dkx492.
5. Bratzler DW, Dellinger EP, Olsen KM, et al. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Am J
Health Syst Pharm. 2013;70:195-283.
6. Scottish Intercollegiate Guidelines Network (SIGN). Antibiotic
Prophylaxis in Surgery. Edinburgh, Scotland: SIGN; 2014.
www.sign.ac.uk/sign-104-antibiotic-prophylaxis-in-surgery.
html. Accessed August 8, 2018
7. Indonesian Ministry of Health (IMOH). Pedoman Umum
Penggunaan Antibiotik. Jakarta, Indonesia; 2011. http://www.
binfar.depkes.go.id/dat/Permenkes_Antibiotik.pdf. Accessed
July 26, 2018.
8. Departement/SMF/Ilmu Bedah-RSUD Dr. Soetomo. Pedoman
penggunaan antibiotika di bidang bedah, Surabaya. Surabaya,
Indonesia: RSUD Dr. Soetomo; 2009.
9. Radji M, Aini F, Fauziyah S. Evaluation of antibiotic prophylaxis administration at the orthopedic surgery clinic of
tertiary hospital in Jakarta, Indonesia. Asian Pac J Trop Dis.
2014;4(3):190-193.
10. Radji M, Fathni R, Fauziyah S. Evaluation of surgical antibiotic prophylaxis in tertiary care hospital in Jakarta Indonesia.
Exp. 2014;18:1292-1296.
11. Syachroni S. Antibiotic prophylaxis compliance for cleancontaminated wounds in a district hospital in Jakarta. HSJI.
2015;6(1):57-62.
12. Amelia E, Arianto B, Purnamayanti A. The suitability and
efficacy of peri operative antibiotics in relation with the surgical wound after appendectomy. Int J Pharm Med Biol Sci.
2016;5(4):222-226.
13. Anonymous. ATC/DDD Index 2017. Date unknown. https://
www.whocc.no/atc_ddd_index/. Accessed July 26, 2018.
14. WHO International Working Group for Drug Statistics
Methodology, WHO Collaborating Centre for Drug Statistics
Methodology & WHO Collaborating Centre for Drug
Utilization Research and Clinical Pharmacological Services.
Geneva: World Health Organization; 2003. http://www.who.
int/iris/handle/10665/42627. Accessed August 8, 2018.
15. Tita ATN, Rouse DJ, Blackwell S, Saade GR, Spong CY,
Andrews WW. Evolving concepts in antibiotic prophylaxis
for caesarean delivery: a systematic review. Obstet Gynecol.
2010;113(3):675-682.
16. Rodríguez-Pardo D, Pigrau C, Corona PS, Almirante B. An
update on surgical and antimicrobial therapy for acute periprosthetic joint infection: new challenges for the present and
the future. Expert Rev Anti Infect Ther. 2015;13(2):249-265.
17. Hadi U, Duerink DO, Lestari ES, et al. Audit of antibiotic prescribing in two governmental teaching hospitals in Indonesia.
Clin Microbiol Infect. 2008;14(7):698-707. doi:10.1111/
j.1469-0691.2008.02014.x.
18. Sözen H, Gönen I, Sözen A, Kutlucan A, Kalemci S, Sahan M.
Application of ATC/DDD methodology to evaluate of antibiotic use in a general hospital in Turkey. Ann Clin Microbiol
Antimicrob. 2013;12(23):2-7.
19. Sweileh WM, Adas SO, Sawalha AF, Taha AS. Utilization and
cost of antibacterial drugs in 2 general surgery units in Palestine
measured using anatomical therapeutic chemical classification


http://www.sign.ac.uk/sign-104-antibiotic-prophylaxis-in-surgery http://www.binfar.depkes.go.id/dat/Permenkes_Antibiotik.pdf http://www.binfar.depkes.go.id/dat/Permenkes_Antibiotik.pdf https://www.whocc.no/atc_ddd_index/ https://www.whocc.no/atc_ddd_index/ http://www.who.int/iris/handle/10665/42627 http://www.who.int/iris/handle/10665/42627 https://www.orcid.org/0000-0002-8355-955X http://www.who.int/drugresistance/documents/surveillancereport/en http://www.who.int/drugresistance/documents/surveillancereport/en

Hospital Pharmacy - October 2019

Table of Contents for the Digital Edition of Hospital Pharmacy - October 2019

TOC/Verso
Disrespectful Behavior in Health System Pharmacy Practice: Consequences and Next Steps
The Orphan Drug Act: An Appropriate Approval Pathway for Treatments of Rare Diseases?
Significant Published Articles for Pharmacy Nutrition Support Practice in 2018
Impact of Delayed Oral Vancomycin for Severe Clostridium difficile Infection
Evaluation of a Hospital Pharmacist Annual Competency Program
A Retrospective Analysis of Adherence to Risk Evaluation and Mitigation Strategies Requirements for Pulmonary Arterial Hypertension Drugs
Impact of an Advanced Pharmacy Practice Experience Student-Run “Meds 2 Beds” and Discharge Counseling Program on Quality of Care
A Retrospective Surveillance of the Antibiotics Prophylactic Use of Surgical Procedures in Private Hospitals in Indonesia
Stability and Compatibility of Diphenhydramine Hydrochloride in Intravenous Admixtures: A New Look at an Old Drug
The Impact of an Automated Dispensing System for Supplying Narcotics in a Surgical Unit: The Experience of the National Cancer Institute Foundation of Milan
Hospital Pharmacy - October 2019 - Cover1
Hospital Pharmacy - October 2019 - Cover2
Hospital Pharmacy - October 2019 - 277
Hospital Pharmacy - October 2019 - TOC/Verso
Hospital Pharmacy - October 2019 - 279
Hospital Pharmacy - October 2019 - Disrespectful Behavior in Health System Pharmacy Practice: Consequences and Next Steps
Hospital Pharmacy - October 2019 - 281
Hospital Pharmacy - October 2019 - 282
Hospital Pharmacy - October 2019 - The Orphan Drug Act: An Appropriate Approval Pathway for Treatments of Rare Diseases?
Hospital Pharmacy - October 2019 - 284
Hospital Pharmacy - October 2019 - Significant Published Articles for Pharmacy Nutrition Support Practice in 2018
Hospital Pharmacy - October 2019 - 286
Hospital Pharmacy - October 2019 - 287
Hospital Pharmacy - October 2019 - 288
Hospital Pharmacy - October 2019 - 289
Hospital Pharmacy - October 2019 - 290
Hospital Pharmacy - October 2019 - 291
Hospital Pharmacy - October 2019 - 292
Hospital Pharmacy - October 2019 - 293
Hospital Pharmacy - October 2019 - Impact of Delayed Oral Vancomycin for Severe Clostridium difficile Infection
Hospital Pharmacy - October 2019 - 295
Hospital Pharmacy - October 2019 - 296
Hospital Pharmacy - October 2019 - 297
Hospital Pharmacy - October 2019 - 298
Hospital Pharmacy - October 2019 - 299
Hospital Pharmacy - October 2019 - Evaluation of a Hospital Pharmacist Annual Competency Program
Hospital Pharmacy - October 2019 - 301
Hospital Pharmacy - October 2019 - 302
Hospital Pharmacy - October 2019 - 303
Hospital Pharmacy - October 2019 - 304
Hospital Pharmacy - October 2019 - 305
Hospital Pharmacy - October 2019 - 306
Hospital Pharmacy - October 2019 - 307
Hospital Pharmacy - October 2019 - 308
Hospital Pharmacy - October 2019 - A Retrospective Analysis of Adherence to Risk Evaluation and Mitigation Strategies Requirements for Pulmonary Arterial Hypertension Drugs
Hospital Pharmacy - October 2019 - 310
Hospital Pharmacy - October 2019 - 311
Hospital Pharmacy - October 2019 - 312
Hospital Pharmacy - October 2019 - 313
Hospital Pharmacy - October 2019 - Impact of an Advanced Pharmacy Practice Experience Student-Run “Meds 2 Beds” and Discharge Counseling Program on Quality of Care
Hospital Pharmacy - October 2019 - 315
Hospital Pharmacy - October 2019 - 316
Hospital Pharmacy - October 2019 - 317
Hospital Pharmacy - October 2019 - 318
Hospital Pharmacy - October 2019 - 319
Hospital Pharmacy - October 2019 - 320
Hospital Pharmacy - October 2019 - 321
Hospital Pharmacy - October 2019 - 322
Hospital Pharmacy - October 2019 - A Retrospective Surveillance of the Antibiotics Prophylactic Use of Surgical Procedures in Private Hospitals in Indonesia
Hospital Pharmacy - October 2019 - 324
Hospital Pharmacy - October 2019 - 325
Hospital Pharmacy - October 2019 - 326
Hospital Pharmacy - October 2019 - 327
Hospital Pharmacy - October 2019 - 328
Hospital Pharmacy - October 2019 - 329
Hospital Pharmacy - October 2019 - Stability and Compatibility of Diphenhydramine Hydrochloride in Intravenous Admixtures: A New Look at an Old Drug
Hospital Pharmacy - October 2019 - 331
Hospital Pharmacy - October 2019 - 332
Hospital Pharmacy - October 2019 - 333
Hospital Pharmacy - October 2019 - 334
Hospital Pharmacy - October 2019 - The Impact of an Automated Dispensing System for Supplying Narcotics in a Surgical Unit: The Experience of the National Cancer Institute Foundation of Milan
Hospital Pharmacy - October 2019 - 336
Hospital Pharmacy - October 2019 - 337
Hospital Pharmacy - October 2019 - 338
Hospital Pharmacy - October 2019 - 339
Hospital Pharmacy - October 2019 - 340
Hospital Pharmacy - October 2019 - 341
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Hospital Pharmacy - October 2019 - 344
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