Hospital Pharmacy - October 2020 - 296
296
2002
Year
* Strategy
C: Intermittent
PPI. Acute treatment with
a PPI (eg, omeprazole 20
mg or lansoprazole 30 mg
once daily) for 4 weeks and
no further treatment with
prescription medications
until recurrence.
Methodology
* Using
a decisionanalytic model,
the calculated
incremental cost
per QALY in
CDN$ is 12 206.
Outcome
Limitation
* Incremental
* For the symptom relief and symptom recurrence meta-analyses, a
cost per QALY
majority of studies relied on endoscopy results as a primary entry
CDN$12 206
criterion and outcome measure, whereas symptoms were typically a
secondary criterion.
* The authors used moderate-to-severe heartburn as primary measure
of GERD symptoms.
* 1-year time horizon for the study may be too short to capture longterm complications such as Barrett esophagus or esophageal stricture.
* This study used inputs (ie, costs), which are specific to the province of
Ontario only.
Conclusion
Note. PPI = proton pump inhibitor; QALYs = quality-adjusted life in years; GERD = gastroesophageal reflux disease.
Goeree et al11
(Canada)
Author
Table 3. Cost-effectiveness of Intermittent PPI Treatment.
Hospital Pharmacy - October 2020
Table of Contents for the Digital Edition of Hospital Pharmacy - October 2020
TOC/Verso
Hospitalization and Combined Use of Opioids, Benzodiazepines, and Muscle Relaxants in the United States
Cost-effective Analysis of Proton Pump Inhibitors in Long-term Management of Gastroesophageal Reflux Disease: A Narrative Review
Evaluating Pharmacy Practice in Hospital Settings in Jeddah City, Saudi Arabia: Prescribing and Transcribing—2018
Formulation and Stability Study of Omeprazole Oral Liquid Suspension for Pediatric Patients
Comparison of 3 Surveillance Methods to Detect Potential Controlled Substance Diversion in an Academic Medical Center
Compatibility of Y-Site Injection of Meropenem Trihydrate With 101 Other Injectable Drugs
A Case of Antibiotic-Induced Posterior Reversible Encephalopathy Syndrome
Hospital Pharmacy - October 2020 - TOC/Verso
Hospital Pharmacy - October 2020 - Cover2
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Hospital Pharmacy - October 2020 - Hospitalization and Combined Use of Opioids, Benzodiazepines, and Muscle Relaxants in the United States
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Hospital Pharmacy - October 2020 - Cost-effective Analysis of Proton Pump Inhibitors in Long-term Management of Gastroesophageal Reflux Disease: A Narrative Review
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Hospital Pharmacy - October 2020 - Evaluating Pharmacy Practice in Hospital Settings in Jeddah City, Saudi Arabia: Prescribing and Transcribing—2018
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Hospital Pharmacy - October 2020 - Formulation and Stability Study of Omeprazole Oral Liquid Suspension for Pediatric Patients
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Hospital Pharmacy - October 2020 - Comparison of 3 Surveillance Methods to Detect Potential Controlled Substance Diversion in an Academic Medical Center
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Hospital Pharmacy - October 2020 - Compatibility of Y-Site Injection of Meropenem Trihydrate With 101 Other Injectable Drugs
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Hospital Pharmacy - October 2020 - A Case of Antibiotic-Induced Posterior Reversible Encephalopathy Syndrome
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