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Otolaryngology-Head and Neck Surgery 163(1S)
Presentation schedule is subject to change. The Official Program Abstracts supplement does not reflect changes made after August 10, 2020.
complete picture of a chronic ear's functional status. It is a
10-point scale with 5 criteria: cochlea (hearing), otorrhea, aeration, cholesteatoma, and happiness ranked from 0 to 2.
Retrospective chart review of 33 patients has shown that the
COACH score significantly improves when comparing preoperative values with those following surgery for chronic ear disease. This study seeks to prospectively validate the COACH
score by assessing correlation with other validated scoring systems such as the middle ear risk index (MERI) and chronic ear
score (CES).
Methods: Prospective cohort study. Patients enrolled undergoing surgery for chronic ear disease from December 1, 2018,
to December 1, 2019, at SUNY Downstate Medical Center.
Preoperative COACH scores calculated and correlation with
MERI and CES assessed.
Results: Ten patients were included in the study. There were
9 male and 1 female, with 5 surgeries performed on left and
right ears each. The mean preoperative COACH score was 2.7
(range 0-7, SD 2.1). The mean MERI score was 5.2 (range
2-9, SD 2.6), and the mean CES was 39.4 (range 20-55, SD
10.8). Preoperative COACH score was negatively correlated
with MERI score (Spearman rho = −0.75, P = .012) and CES
(Spearman rho = −0.70, P = .035).
Conclusions: The COACH score is a novel chronic ear grading system that can become a standardized instrument for
evaluating a chronic ear. We have demonstrated that patients
who have had surgery for cholesteatoma have COACH scores
that negatively correlate with scores for MERI and CES. This
finding suggests that the COACH score is predictive of the
health and functional status of the middle ear.
Otology/Neurotology
Quantifying Type 1 Afferent Cochlear
Synapses in Experimental Endolymphatic
Hydrops
Carla V. Valenzuela, MD (Presenter); Choongheon Lee, PhD;
Shawn S. Goodman, PhD; Amanda J. Ortmann, PhD;
Craig A. Buchman, MD; Mark A. Rutherford, PhD;
Jeffery T. Lichtenhan, PhD
Objectives: Endolymphatic hydrops (EH) is an enlargement
of scala media. EH is associated with low-frequency sensorineural hearing loss but the origin remains unknown. Cochlear
synapse loss could represent an origin; however, it has not
been fully assessed in EH. Our objective was to quantify the
number of cochlear synapses in experimental EH.
Methods: Surgical ablation of the endolymphatic sac was
performed on the right ear of 16 guinea pigs. The left (nonoperated) ear served as the control. We have previously demonstrated the efficacy of this procedure in inducing histologically
measurable EH by postoperative day (POD) 30. Objective measurements of hearing were made on POD 1, 4, and 30. Temporal
bones were immediately harvested and prepared for immunohistochemistry to label the presynaptic ribbons (mouse antiCtBP2, 1:200), postsynaptic receptors (mouse anti-PSD95,
1:100), and inner hair cell cytoplasm (rabbit anti-MYO7A,
1:400) with species-appropriate, Alexa Fluor-coupled, secondary antibodies. Thus far, paired synapses in cochlear turns I and
III have been quantified manually by 2 blinded counters for
POD 4 and 30.
Results: Data analysis is ongoing. The interclass correlation
coefficient between the 2 counters for POD 4 and 30 was 97%.
The right ear had low-frequency (0.3-4 kHz) hearing loss
assessed with the Auditory Nerve Overlapped Waveform and
no permanent change to high-frequency (>4 kHz) hearing
function as assessed with cochlear compound action potentials and distortion product otoacoustic emissions amplitudes.
Synaptic counts did not differ between the right and left ears
for POD 4 and 30.
Conclusions: These results demonstrate that low-frequency
hearing loss in ears with EH does not originate from cochlear
synaptopathy.
Quantitative Analysis of the Peripheral
Cochlear and Vestibular Ganglion Neurons
in Temporal Bones With Serous Otitis
Media
Rafael C. Monsanto, MD (Presenter);
Norma de Oliveira Penido, MD, PhD; Mio Uchiyama;
Michael M. Paparella, MD; Sebahattin Cureoglu, MD
Objectives: Quantitative data referring to the analysis of spiral or Scarpa ganglion cells in serous otitis media (SOM) are
scarce and inconclusive. Therefore, the objective of this study
is to determine whether or not SOM leads to loss of spiral and
Scarpa ganglion neurons as compared with controls.
Methods: From the human temporal bone (HTB) collection
at the University of Minnesota, we selected HTBs with chronic
otitis media, defined as the presence of serous effusion (presence of a pale effusion, constituting a yellow exudate, with low
viscosity) in the middle ear cleft. We also selected HTBs from
donors with no ear diseases as controls. We quantitatively analyzed the number of spiral and Scarpa ganglion cells and compared the results obtained in the control and study groups.
Results: Our final group of temporal bones comprised
10 HTBs with SOM and 10 age- and sex-matched controls. In
both SOM and control groups, we observed a significant
strong negative correlation between age and number of both
spiral (R = −0.664; P < .001) and Scarpa ganglion (R = −0.420;
P = .026) cells. In the HTBs with SOM, the presence of
cochlear or vestibular hydrops, serous labyrinthitis, hyperplastic middle ear mucosa, or tympanic membrane abnormalities was not associated with increased loss of peripheral
vestibular or cochlear ganglion neurons (P > .05). We did not
find any significant differences in the number of spiral ganglion cells (in total or per segment) or the density of Scarpa
ganglion cells (in each vestibular nerve or both) in the SOM
group as compared with controls (P > .05).
Conclusions: Our results did not demonstrate significant loss
of cochlear or vestibular peripheral ganglion neuron loss in
HTBs with SOM as compared with controls.
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts
Table of Contents for the Digital Edition of Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts
Contents
Accreditation Information
2020 President Duane J. Taylor, MD
2020 Annual Meeting Program Committee
2020 Star Reviewers
2020 Distinguished Service Award Recipients
2020 Honor Award Recipients
Honorary Guest Lecturers 2020
Panel Presentations
Oral Presentations
Poster Presentations
Author Index
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Intro
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Cover2
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - A1
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - A2
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - A3
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Contents
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - A5
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - A6
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Accreditation Information
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - 2020 President Duane J. Taylor, MD
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - 2020 Annual Meeting Program Committee
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P4
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - 2020 Star Reviewers
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - 2020 Honor Award Recipients
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P7
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Honorary Guest Lecturers 2020
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P9
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Panel Presentations
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Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Oral Presentations
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Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P269
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Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P271
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P272
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P273
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P274
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P275
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P276
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P277
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P278
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P279
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P280
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P281
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P282
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P283
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P284
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P285
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P286
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P287
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P288
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P289
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P290
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P291
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P292
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P293
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P294
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P295
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P296
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P297
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P298
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P299
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P300
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P301
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P302
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P303
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P304
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P305
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P306
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P307
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P308
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P309
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P310
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P311
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P312
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Author Index
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P316
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P317
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P318
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P319
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P320
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P321
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P322
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P323
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P324
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P325
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P326
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P327
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P328
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P329
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P330
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P331
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P332
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Cover3
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Cover4
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