Magnetics Business & Technology - September/October 2023 - 4

EDITOR'S CHOICE
Phantech Advances MRI Precision with Magnetic Phantoms
Magnetic particle imaging using Phantech spiral
resolution phantom
Precision and purity are both key elements
for successful magnetic resonance
imaging in today's medical and scientific
worlds. One company advancing the technology
is startup biotech firm Phantech, a
spinout from laboratories at the University
of Wisconsin which specializes in creating
preclinical and clinical phantoms used
for calibrating sensitive MRI equipment.
Among its types of phantoms are several
for the growing field of magnetic particle
imaging.
Basically, a phantom is a specially designed
object that is utilized as a stand-in for human tissue and can be scanned or imaged
to evaluate, analyze and fine-tune the performance of an imaging device. Phantech offers
spiral and multi-purpose phantoms to characterize the resolution of a superparamagnetic
iron oxide nanoparticle (SPION) with a specific magnetic particle imaging system. The
image at top, for example, shows magnetic particle imaging of Synomag-D particles with
hydrodynamic diameters of 50nm using Phantech's spiral resolution phantom.
It is critical that MPI phantoms do not contain any
metal contaminants that are present in most plastics
in order to measure the true resolution and linearity
of a SPION and MPI system. One innovation by the
team of molecular imaging researchers, biomedical
engineers and imaging scientists has been to develop
a patented linear filling technology to overcome the
presence of bubbles that can compromise imaging
accuracy.
Linear filling is achieved through a piece-wise construction
that creates a long snaking channel through the
desired phantom. This chain is comprised of both the hot
rods that comprise the desired hole pattern, as well as
connecting channels to connect neighboring hot rods.
With a single inlet and outlet, fluid can be easily driven into the phantom, eliminating the need to
manually fill small holes that are prone to air bubbles from surface tension.
Magnetic particle Imaging multipurpose
phantom
Volume 22, Issue 5
Editor & Publisher
David Webster
Contributing Editor
Dr. Stan Trout
Director of Operations and
Support Services
Ross Webster
Director of Sales and Content
Scott Webster
Design & Layout
Scott Webster
Administration
Marsha Grillo
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Innovative linear filling to enhance accuracy
Located in Madison, Wisconsin, one of Phantech's activities now is to partner with manufacturers
of biomedical imaging systems by creating customizable sets of phantoms tailored to particular
imaging platforms. In June, it showcased its technology at the 2023 annual meeting of the Society
for Nuclear Medicine & Molecular Imaging in Chicago.
For more info, see www.phantechmedical.com.
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Magnetics Business & Technology - September/October 2023

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