Medical Design Briefs - October 2022 - 40

Y-type fiber
Multiplexed
optical fiber
sensor
Light source
Spectrometer
Microcomputer
The device comprises a flexible silica-based optical fiber that is inserted into brain tissue to monitor the cerebrospinal fluid (CSF).
between the different stages of TBI simulated
by the researchers.
Dr. Ali Yetisen, who led the research
team at the department of chemical
engineering, says, " Our study showed
the device's ability to dynamically
monitor multiple biomarkers to assess
metabolic changes in the brain. It
continuously reflects the injury's status,
which could help neurosurgeons
follow the disease course precisely to
make evidence-based clinical decisions
and treatment. "
The researchers continue to develop
the sensor by using optical bundles to
expand the range of testable biomarkers,
such as inflammatory agents and
neurotransmitters. They are also developing
a more complex machine learning
system to make the most of the data
and predictive mechanisms available.
They also note that more tests using living
animals are needed to assess a whole
body's response to the probe, and to test
the ability of the fiber sensor in real-case
applications.
This research was funded by the Royal
Society and the Royal Society of Chemistry.
This article was written by Caroline
Brogan, Imperial College London.
For more information, visit www.
imperial.ac.uk. Contact: caroline.brogan
@imperial.ac.uk.
Ultrathin Dental Camera Inspired by Insect-Eye Structure
Biologically inspired camera
achieves diverse functional
dental imaging with high
dynamic range, 3D depth,
and autofluorescence.
SPIE
Bellingham, WA
Conventional dental photography technology
has had a limitation in using inconvenient
tools such as mirrors and cheek
retractors. Dentists require basic teeth images
from various angles, such as right/left
buccal and maxillary/mandibular occlusal,
for dental health inspection. To acquire
these images, patients feel discomfort
because dentists must put a mirror
into the mouth to capture the reflected
teeth image through a handheld camera.
Information such as tooth arrangement
and the location of tooth decay can be obtained
through this process. A compact
intraoral dental camera can overcome the
40
Convex prism
HDR recon.
discomfort and scan the condition of
teeth. However, due to the restricted depth
of field and field of view, the conventional
device has limitations in close-up imaging
for observing tooth decay in detail and
wide-angle imaging for capturing the entire
arrangement of teeth.
Various species of compound insect
eyes have superior visual characteristics,
such as wide viewing angle and large
depth of field with compact visual organs
made up of tiny lenses. Insect eyes give
inspiration for miniaturized cameras,
and insect-inspired cameras can solve the
Spacers
iMLAs
autofluorescence
LED
Frame
Images sensor w/FPCB
3D depth map
A fully packaged ultrathin dental camera and multifunctional dental images. (Credit: doi 10.1117/1.
JOM.2.3.031202)
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Medical Design Briefs, October 2022
Estimated distance (mm)
810 12 14

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Medical Design Briefs - October 2022

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