Medical Design Briefs - October 2022 - 41

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Various types of intraoral camera prototypes for usability
testing. (Credit: doi 10.1117/1)JOM.2.3.031202)
problems of conventional compact cameras,
such as limited observation range.
However, previously
developed
insect
cameras have drawbacks in low- resolution
or limited functions.
As reported in the Journal of Optical
Microsystems, researchers from Korea Advanced
Institute of Science and Technology
and Korea Photonics Technology
Institute recently developed a novel
wide-angle insect eye camera, the biologically
inspired
intraoral camera
(BIOC), for assorted functional imaging.
Using the device, assorted functional
imaging was demonstrated to satisfy
clinical needs.1
The BIOC involves a new configuration
of convex-concave lens and inverted
microlens arrays (iMLA) and a single
CMOS image sensor on a flexible
printed circuit board in a handpiece
holder. The convex-concave lens substantially
increases the field of view up
to 143°, and iMLAs reduce optical aberration
by the scaling law. In addition,
the new camera overcomes many
chronic issues of conventional intraoral
cameras, such as limited depth of field,
thick total-track-length, and limited
functional imaging. In detail, the ultrathin
dental camera can solve discomfort
states owing to its thinness and observe
teeth even in anatomically narrow
regions. Also, clear dental imaging is
achieved without image blur by emulating
the insect vision feature of infinite
depth of field even at close object distance.
The BIOC offers multifunctional
dental imaging, such as high dynamic
range, 3D depth, and autofluorescence
imaging, through the multichannel vision
system.
The authors hope that the novel
wide-angle insect eye camera contributes
not only technical advances in biomedical
engineering societies but that it also
has significant impacts on such diverse
vision applications as surveillance, smartphone,
and drones. They anticipate a
continuing expansion in applications in
the future.
Reference
1. K. Kim et al., " Biologically inspired intraoral camera
for multifunctional dental imaging, " J. Opt.
Microsystems 2(3) 031202 (2022), doi 10.1117/1.
JOM.2.3.031202.
For more information, visit https://
spie.org. Contact: Dr. Kisoo Kim, KAIST,
kisoo.kim1@kaist.ac.kr.
Building Better Gas-Phase Biosensors
for Fight Against Diseases
The electrospun polymer
mesh biosensor can
detect volatile organic
compounds.
Tokyo Medical and Dental
University
Tokyo, Japan
Scientists have introduced an easy
method for manufacturing biosensors
made from electrospun polymers. By
embedding enzymes inside the polymer
string, the enzymes were operational
even in a dry state. These biosensors
can be used to screen certain diseases,
Medical Design Briefs, October 2022
as well as to monitor environments for
specific chemical compounds in the air.
Enzymes are biological catalysts that
allow many chemical reactions vital for
life to progress much faster than they
normally would. One of the remarkable
features of some enzymes is their
strong specificity, in which the reaction
will work with certain target molecules,
but not with even very similar ones.
Scientists have known for a long time
that these properties can be utilized
to create highly sensitive and accurate
biosensors for specific substances, including
those associated with the disease.
However, most conventional biosensors
require keeping the enzyme in
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41
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Medical Design Briefs - October 2022

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