Medical Design Briefs - August 2023 - 6

Manufacturing Considerations
for Implantable
Drug-Delivery Systems
T
herapy developers are being asked to consider ways
to deliver drugs for a longer time period with a single
dose. This has spurred innovation in both the
oral and parenteral spaces, but the greatest potential
for long-acting delivery remains in implantable
systems. Because of this, growth for the global implantable
drug-delivery market is forecast at 10 percent annually in coming
years with an expectation for the
market to reach nearly $30 billion
(USD) by 2025.1 Contraceptive,
ophthalmic, cardiovascular, diabetes,
oncology, and autoimmune
disease applications
are all likely to focus on
development of these
therapeutic forms.
Pharmaceutical companies that embrace drug-elution technologies
are better equipped to solve patient compliance issues
through longer-term delivery of a therapy. They are also able to
design a targeted therapy that may lower the required dosage
of a given drug, which can help limit side effects for patients.
These advantages mean many patients living with chronic conditions
can realize significant improvements in their overall
quality of life.
Although the advantages of implantable drugdelivery
systems are undeniable, therapy producers
often view the design process for
Whether minimizing the needle
gauge used to insert the implant or
making the implant procedure less
invasive, smaller drug systems
provide a distinct advantage.
(Credit: Trelleborg)
6
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Medical Design Briefs - August 2023

Table of Contents for the Digital Edition of Medical Design Briefs - August 2023

Medical Design Briefs - August 2023 - COV1a
Medical Design Briefs - August 2023 - COV1b
Medical Design Briefs - August 2023 - COV1
Medical Design Briefs - August 2023 - COV2
Medical Design Briefs - August 2023 - 1
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