Medical Design Briefs - October 2024 - 13
Finding a Patch Partner
Look for a company that can deliver
HCI salts through the skin, has patent-protect
platform technologies, manages
complex development issues, and
provides experts in product development
and commercial manufacturing.
There are at least three ways to work
with a patch partner. The first, moving a
product from ground zero, or as an idea
of a drug molecule, involves taking early-stage
molecules from concept across
multiple different therapeutic areas.
This can involve:
* Product concepts across multiple therapeutic
areas.
* Feasibility and prototyping work through
commercial manufacturing.
* Exclusive use of patented formulation
solutions for intellectual property
protection through the year 2042
or beyond.
The second way to work together with
a patch partner is for companies with
a clinical asset that have demonstrated
product opportunities but require manufacturing
and development support
Corplex®
, which has a proprietary mix of adhesives,
polymers, and liners, is used in the contraceptive
Twirla. (Credit: Corium Innovations)
and access to the intellectual property,
patents and innovation.
The third and final method works
for companies with the opportunity to
transfer technology or need a secondary
manufacturing source so as to mitigate
the risk in terms of supply chain.
Wherever a company is in the development
of a delivery-system process, a
transdermal patch should be considered
when patient compliance and efficacy
are required.
Reference
1. M Pastore, et al., " Transdermal patches: history,
development and pharmacology, " Br J Pharmacol.,
2015 May; 172(9): 2019: 2179-2209,
https://www.ncbi.nlm.nih.gov/pmc/articles/
PMC4403087.
This article was written by Niraj Vasisht,
PhD, Chief Technology Officer
of Corium Innovations, Grand Rapids,
MI. Corium Innovations, a full-service
contract development and manufacturing
organization, focusing on the
development and manufacturing of
transdermal patches and transmucosal
films. With more than 30 years' experience
in the pharmaceutical industry,
For more information, e-mail Kevin
Ostrander at bizdev@coriumintl.com
or visit www.coriuminv.com.
Medical Design Briefs, October 2024
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1/9/23 10:19 AM
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403087
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Medical Design Briefs - October 2024
Table of Contents for the Digital Edition of Medical Design Briefs - October 2024
Medical Design Briefs - October 2024 - COVTIP
Medical Design Briefs - October 2024 - COVFLAP
Medical Design Briefs - October 2024 - COV1
Medical Design Briefs - October 2024 - COV2
Medical Design Briefs - October 2024 - 1
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