Medical Design Briefs - October 2024 - 43

There are gaps between the wavelengths,
and the jump between 1064 nm
to 532 nm is significant, adding that testing
each of those harmonics increases
the cost. OPO lasers can convert the fundamental
wavelength of pulsed mode
Nd:YAGs to a selected frequency. This
tunability enables OPOs to generate
light in a broad range of wavelengths
that are amplified within the OPO for a
usable output beam.
An OPO laser can be tuned to a very
specific wavelength resolution by simply
punching in a number like 410, 410.1, or
410.2 nanometers. These pulse-based
OPO lasers can deliver concentrated energy
in short durations measured in
nanoseconds making them ideal for
nanosecond time resolved spectroscopy.
McCusker and his research group use
the Vibrant 355 II Nd:YAG-pumped
OPO laser from OPOTEK, which can
quickly provide a tunable wavelength
output from 300 to 2400 nm and is used
for both time-resolved absorption and
time-resolved emission requirements.
These lasers include software applications,
which has made them more
user-friendly.
Reaching into Deep UV
Much of the research conducted by
McCusker and his team involves designing
and synthesizing molecules
that absorb light in the visible part of
the spectrum. However, he notes that
for organic carbon-based or aromatic
compounds, researchers may want to
study UV damage to DNA. Since DNA
is composed of organic base pairs that
absorb in the ultraviolet spectrum rather
than the visible spectrum, OPO lasers
are required to access those ultraviolet
wavelengths for the study of
these compounds.
OPO lasers can be designed to generate
wavelengths down to 190 nanometers
through multiple stages of optical
conversion. Moreover, unlike typical
fixed wavelength deep UV lasers, OPO
lasers are solid-state and so do not require
expensive consumables such as
specialized gas or chemical mixtures as
the lasing medium.
Future time-resolved spectroscopic
research by academic research labs will
continue to rely on the flexibility and
tunability of OPO lasers to further their
knowledge of how materials transmit,
absorb, and reflect light.
This article was written by Dr. Mark
Little, Technical and Scientific Consultant
for OPOTEK, Carlsbad, CA. For
more information, call 760-929-0770 or
visit www.opotek.com.
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Optical parametric oscillators (OPO) are a notable
type of tunable laser, now a commercial reality after
35 years of development.
Medical Design Briefs, October 2024
www.medicaldesignbriefs.com
43

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Medical Design Briefs - October 2024

Table of Contents for the Digital Edition of Medical Design Briefs - October 2024

Medical Design Briefs - October 2024 - COVTIP
Medical Design Briefs - October 2024 - COVFLAP
Medical Design Briefs - October 2024 - COV1
Medical Design Briefs - October 2024 - COV2
Medical Design Briefs - October 2024 - 1
Medical Design Briefs - October 2024 - 2
Medical Design Briefs - October 2024 - 3
Medical Design Briefs - October 2024 - 4
Medical Design Briefs - October 2024 - 5
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Medical Design Briefs - October 2024 - COV3
Medical Design Briefs - October 2024 - COV4
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