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Chapter 1: Burden of Digestive Disorders
Pancreatic cancer
For the 44 member countries combined, age-standardised incidence and mortality rates for
pancreatic cancer have increased over time (Figure 110). From 2000-2019, age-standardised
incidence rates increased by around 11% (8.7 to 9.6 per 100,000) and age-standardised
mortality rates also increased by around 11% (8.6 to 9.5 per 100,000). The total number of
incident cases and deaths in the member countries combined increased by around 53%
(101,122 to 154,361) and (101,392 to 155,010), respectively, from 2000-2019.
For the member countries combined, incidence rates increase steadily with age, peaking at
ages 85+ years for women and men (Figure 111). For both sexes combined, age-specific
incidence rates have increased for older age groups (55+ years) from 2000-2019.
Amongst the member countries in 2019, age-standardised incidence rates range from 2.9 to
11 and 4.3 to 14 per 100,000 for women and men, respectively, and age-standardised
mortality rates range from 2.9 to 10 and 4.5 to 15 per 100,000 for women and men,
respectively (Figure 112; Figure 113).
Age-standardised DALY rates for both sexes combined range from 85 to 275 per 100,000
among the member countries (Figure 114). Age-standardised DALY rates are relatively low
amongst member countries within Northern Africa, whilst some of the highest rates occur
among countries within Central and Eastern and Southeastern Europe. Of the 44 countries,
33 (75%) have experienced a percentage change increase in age-standardised DALY rates
from 2000-2019. All member countries within Northern Africa and Southeastern Europe have
experienced percentage change increases in age-standardised DALY rates from 2000-2019, as
have the majority of countries in most other regions (except for the Nordic region).
Proportions of pancreatic cancer age-standardised DALY rates attributable to smoking and
high BMI range from 12-36% and 6-10%, respectively, among the member countries (Figure
115). Proportions of burden attributable to smoking are generally lowest among member
countries within Northern Africa, and highest amongst countries within Southeastern Europe.
Of the 44 countries, 13 (30%) have experienced percentage change increases in the
proportion of burden attributable to smoking, whilst all member countries have experienced
increases in the proportion of burden attributable to high BMI, from 2000-2019. All member
countries within the Nordic region have experienced decreases in the proportion of burden
attributable to smoking over time.
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