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Chapter 1: Burden of Digestive Disorders
Gastroesophageal reflux disease
For the 44 member countries combined, trends in age-standardised incidence and prevalence
rates for gastroesophageal reflux disease have remained relatively stable over time (Figure
59). From 2000-2019, age-standardised incidence rates increased by around 2% (4230 to
4301 per 100,000) and age-standardised prevalence rates also increased by around 2%
(10,727 to 10,943 per 100,000). The total number of incident and prevalent cases in the
member countries combined has increased by around 17% (43,031,060 to 50,553,564) and
19% (109,746,619 to 130,795,777), respectively from 2000-2019.
For the member countries combined, prevalence rates for gastroesophageal reflux disease
peak at ages 65-74 and 70-79 years for women and men, respectively, but tend to also be
high amongst those of working age (Figure 60). Age-specific prevalence rates are higher for
women across all age groups. For both sexes combined, age-specific prevalence rates have
remained relatively stable from 2000-2019 for most age groups, but have increased slightly
among younger age groups.
Amongst the member countries in 2019, age-standardised incidence rates range from 2217
to 5780 and 1914 to 4955 per 100,000 for women and men, respectively (Figure 61). Agestandardised
prevalence rates range from 5112 to 16,130 and 4190 to 13,100 per 100,000 for
women and men, respectively (Figure 62).
Age-standardised DALY rates for both sexes combined range from 36 to 110 per 100,000
among the member countries (Figure 63). Amongst the member countries, some of the
highest estimated age-standardised DALY rates are experienced by countries within Western
Asia, Northern Africa and Central and Eastern Europe. Of the 44 member countries, 23 (52%)
have experienced either a percentage change increase or no change in age-standardised
DALY rates from 2000-2019. France, Spain and Turkey experienced the largest percentage
change increase in age-standardised DALY rates from 2000-2019, of the member countries,
whilst the UK experienced the largest percentage change decrease in age-standardised DALY
rates over the same period.
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