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Chapter 1: Burden of Digestive Disorders
CHAPTER 1: BURDEN OF DIGESTIVE
DISORDERS
Continued monitoring of the burden of digestive disorders at a national level is needed to
inform prioritisation and address evolving challenges. Examining how the burden changes
over time by disease and country may help to enhance our understanding of the changing
epidemiology of digestive disorders and how this may influence future needs. Additionally,
the latest evidence indicating the extent of preventable burden is needed to identify where
the greatest health gains can be made. Monitoring trends in the proportion of burden
attributable to modifiable risk factors may also help to identify where interventions and
prevention strategies have been effective in achieving sustained reductions in burden.
This chapter provides an international comparative analysis of the public health burden of
digestive disorders to help address these needs. We present estimates of the distribution of
the overall burden of digestive diseases and cancers, as well as disease specific estimates for
UEG national society member countries, using measures such as incidence, prevalence,
mortality, and disability-adjusted life year (DALY) rates, and presenting changes in these
measures since the year 2000. We also examine the proportions of DALY rates attributable to
modifiable risk factors, where this information is available. Estimates produced by the Global
Burden of Disease Study (GBD) 20191 are utilised, alongside data obtained from published
literature. We present a general overview, and more detailed country-specific data can be
accessed via the GBD Results Tool.1 Details of the methods and data sources can be found in
the Appendix.
To begin, we provide a summary of the overall estimated burden of digestive diseases and
cancers across 44 UEG member countries, located within Europe, Western Asia and Northern
Africa, highlighting changes in the burden of digestive disorders since the turn of the century.
Digestive diseases
Digestive diseases are common and contribute to increasing levels of burden amongst UEG
member countries. Estimates from GBD 20191 suggest that from 2000-2019, the total
number of incident cases, deaths and prevalent cases have increased by around 17%, 20%
and 22%, respectively, for the member countries combined (Figure 1). In 2019, there were
72,272,902 incident cases, 497,653 deaths and 332,191,552 prevalent cases amongst the
member countries.
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